Systemic chronic inflammation (SCI) is persistent, health-damaging, low-grade inflammation
that plays a major role in immunosenescence and in development and progression of many …

Nanoscale fluorescence emitters are efficient for measuring biomolecular interactions, but
their utility for applications requiring single-unit observations is constrained by the need for …

While nanoscale quantum emitters are effective tags for measuring biomolecular
interactions, their utilities for applications that demand single-unit observations are limited by …

Extracellular vesicles (EV) are small membrane-bound structures that are secreted by
various cell types, including tumor cells. Recent studies have shown that EVs are important …

Circulating nucleic acids are found in free form in body fluids and may serve as minimally
invasive tools for cancer diagnosis and prognosis. Only a few studies have investigated the …

MicroRNAs (miRNAs) are secreted by cells in vesicles, bound in a ribonucleoprotein
complex or as free molecules. These miRNA secretion pathways are dysregulated in cancer …

Exosomes (Exos) have been reported to promote pre-metastatic niche formation,
proliferation, angiogenesis and metastasis. We have investigated the role of uPAR in …

Background Novel and non-invasive biomarkers with higher sensitivity and specificity for the
diagnosis of prostate cancer (PCa) is urgently needed. In this study, we used next …

Prostate cancer (PC) is a very important kind of male malignancies. When PC evolves into a
stage of hormone resistance or metastasis, the fatality rate is very high. Currently …

MiR-375 is a conserved noncoding RNA that is known to be involved in tumor cell
proliferation, migration, and drug resistance. Previous studies have shown that miR-375 …