Platinum-based chemotherapy in metastatic prostate cancer: what possibilities?

M Catalano, A Lapucci, S Nobili… - Cancer Chemotherapy …, 2024 - Springer
Metastatic prostate cancer is a major health burden worldwide, necessitating the continuous
development of effective treatment strategies. Androgen deprivation therapy remains the …

Defining oligometastatic state in uro-oncological cancers

T Fazekas, M Miszczyk, A Matsukawa… - Current Opinion in …, 2024 - journals.lww.com
Defining oligometastatic state among urological tumors reflecting their distinct biological and
clinical behavior is crucial to establish a sound framework for future clinical trials, and to …

Role of Lutetium Radioligand Therapy in Prostate Cancer

I Książek, A Ligęza, F Drzymała, A Borek, M Miszczyk… - Cancers, 2024 - mdpi.com
Simple Summary Lutetium-177-PSMA—a radiopharmaceutical composed of a radionuclide
lutetium-177 and a PSMA-binding ligand—is a theranostic medicine for prostate cancer. In …

Platinum Chemotherapy After PARP Inhibition in HRR-Deficient Metastatic Castration-Resistant Prostate Cancer

J Obasi, K Sharma, N De Sarkar, ES Antonarakis… - Clinical Genitourinary …, 2024 - Elsevier
Clinical Practice Points• PARP inhibitors can be efficacious in a selected cohort of prostate
cancer patients with HRD.• A significant fraction of PARP inhibitor resistance occurs due to …

[HTML][HTML] Long term evaluation of optimized Gleason grading in a large cohort of men with prostate cancer in Canada

M Wissing, F Brimo, G McKercher, E Scarlata, F Saad… - Human Pathology, 2024 - Elsevier
Abstract Objectives To evaluate the International Society of Urological Pathology (ISUP) 5-
tier grade grouping (GG) system of prostate cancers as well as previously proposed …

Comprehensive Genomic Profiling of Taiwanese Breast Cancer Using a Novel Targeted Sequencing Panel

CC Huang, YC Yeh, CY Liu, YF Tsai, HL Ho, LM Tseng - 2024 - researchsquare.com
Background Breast cancer is one of the leading causes of cancer-related deaths in women.
Limited therapeutic options currently available, especially for those with triple negative …

[HTML][HTML] Poly (ADP-ribose) Polymerase Inhibitors Have Comparable Efficacy with Platinum Chemotherapy in Patients with BRCA-positive Metastatic Castration …

T Szarvas, P Nyirády, B Hadaschik, T Fazekas - urotoday.com
Advancements in molecular diagnostics and targeted therapies of the past years brought the
era of precision medicine in prostate cancer care. The evolving accessibility and global …