Advances of optical miniscopes for in vivo imaging of neural activity in freely moving animals

K Chen, Z Tian, L Kong - Frontiers in Neuroscience, 2022 - frontiersin.org
To study neural mechanisms of ethologically relevant behaviors including many social
behaviors and navigations, optical miniscopes, which can be carried by the model animals …

Optogenetics 2.0: challenges and solutions towards a quantitative probing of neural circuits

S Altahini, I Arnoux, A Stroh - Biological Chemistry, 2024 - degruyter.com
To exploit the full potential of optogenetics, we need to titrate and tailor optogenetic methods
to emulate naturalistic circuit function. For that, the following prerequisites need to be met …

Distinct ventral hippocampal inhibitory microcircuits regulating anxiety and fear behaviors

K Li, K Koukoutselos, M Sakaguchi… - Nature Communications, 2024 - nature.com
In emotion research, anxiety and fear have always been interconnected, sharing
overlapping brain structures and neural circuitry. Recent investigations, however, have …

A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits

J Wietek, A Nozownik, M Pulin, I Saraf-Sinik… - Nature …, 2024 - nature.com
Abstract Information is transmitted between brain regions through the release of
neurotransmitters from long-range projecting axons. Understanding how the activity of such …

Assembly and operation of an open-source, computer numerical controlled (CNC) robot for performing cranial microsurgical procedures

ML Rynes, L Ghanbari, DS Schulman, S Linn… - Nature protocols, 2020 - nature.com
Cranial microsurgery is an essential procedure for accessing the brain through the skull that
can be used to introduce neural probes that measure and manipulate neural activity …

[HTML][HTML] Functional interrogation of neural circuits with virally transmitted optogenetic tools

B De La Crompe, P Coulon, I Diester - Journal of Neuroscience Methods, 2020 - Elsevier
The vertebrate brain comprises a plethora of cell types connected by intertwined pathways.
Optogenetics enriches the neuroscientific tool set for disentangling these neuronal circuits in …

Recent advances in light patterned optogenetic photostimulation in freely moving mice

A Lorca-Cámara, FGC Blot, N Accanto - Neurophotonics, 2024 - spiedigitallibrary.org
Optogenetics opened the door to a new era of neuroscience. New optical developments are
under way to enable high-resolution neuronal activity imaging and selective …

[PDF][PDF] 双色荧光成像在体微型显微镜

蓝凯秋, 杨西斌徐宝腾, 刘家林, 周伟, 熊大曦 - 光子学报, 2022 - researching.cn
目前微型显微镜光学系统大都采用梯度折射率透镜作为物镜, 受其色差限制,
双色荧光成像效果较差. 首先设计了微型消色差镜头代替梯度折射率透镜 …

Оптогенетические методы и технологии в решении прикладных медицинских задач

ЛЕ Сорокина, ВИ Петренко… - Бюллетень …, 2020 - cyberleninka.ru
Оптогенетика-инновационное и быстро развивающиеся научное направление,
объединяющее достижения молекулярной биологии и лазерных технологий для …

Hippocampal contextualization of social rewards

JM Duarte, K Li, R Nguyen, S Ciocchi - bioRxiv, 2023 - biorxiv.org
Acquiring and exploiting memories of rewarding experiences is critical for survival. The
spatial environment in which a rewarding stimulus is encountered regulates memory …