The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Cerebral edema formation after stroke: emphasis on blood–brain barrier and the lymphatic drainage system of the brain

S Chen, L Shao, L Ma - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Brain edema is a severe stroke complication that is associated with prolonged
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …

Meisoindigo protects against focal cerebral ischemia-reperfusion injury by inhibiting NLRP3 inflammasome activation and regulating microglia/macrophage …

Y Ye, T Jin, X Zhang, Z Zeng, B Ye, J Wang… - Frontiers in cellular …, 2019 - frontiersin.org
Ischemic stroke is a devastating disease with long-term disability. However, the
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …

Modes of brain cell death following intracerebral hemorrhage

Y Zhang, S Khan, Y Liu, R Zhang, H Li, G Wu… - Frontiers in Cellular …, 2022 - frontiersin.org
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high rates of mortality
and morbidity. It induces cell death that is responsible for neurological deficits postinjury …

Linker Design Impacts Antibody-Drug Conjugate Pharmacokinetics and Efficacy via Modulating the Stability and Payload Release Efficiency

D Su, D Zhang - Frontiers in pharmacology, 2021 - frontiersin.org
The development of antibody-drug conjugates (ADCs) has significantly been advanced in
the past decade given the improvement of payloads, linkers and conjugation methods. In …

The specific role of reactive astrocytes in stroke

L Li, J Zhou, L Han, X Wu, Y Shi, W Cui… - Frontiers in Cellular …, 2022 - frontiersin.org
Astrocytes are essential in maintaining normal brain functions such as blood brain barrier
(BBB) homeostasis and synapse formation as the most abundant cell type in the central …

Metagenomic sequencing of diamondback moth gut microbiome unveils key holobiont adaptations for herbivory

X Xia, GM Gurr, L Vasseur, D Zheng, H Zhong… - Frontiers in …, 2017 - frontiersin.org
Herbivore specialists adapt to feed on a specific group of host plants by evolving various
mechanisms to respond to plant defenses. Insects also possess complex gut microbiotas but …

Molecular mechanisms of neuronal death in brain injury after subarachnoid hemorrhage

J Chen, M Li, Z Liu, Y Wang, K Xiong - Frontiers in Cellular …, 2022 - frontiersin.org
Subarachnoid haemorrhage (SAH) is a common cerebrovascular disease with high
disability and mortality rates worldwide. The pathophysiological mechanisms involved in an …

How does inequality affect the residents' subjective well-being: Inequality of opportunity and inequality of effort

Q He, H Tong, JB Liu - Frontiers in Psychology, 2022 - frontiersin.org
Based on the Chinese General Social Survey database (2010–2015), this article explores
the relationship between income inequality and residents' subjective well-being from the …

Ferroptosis, a regulated neuronal cell death type after intracerebral hemorrhage

Q Bai, J Liu, G Wang - Frontiers in Cellular Neuroscience, 2020 - frontiersin.org
Ferroptosis is a term that describes one form of regulated non-apoptotic cell death. It is
triggered by the iron-dependent accumulation of lipid peroxides. Emerging evidence …