Agents that inhibit bacterial biofilm formation
N Rabin, Y Zheng, C Opoku-Temeng, Y Du… - Future medicinal …, 2015 - Taylor & Francis
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …
a biofilm can also survive harsh conditions and withstand the host's immune system …
Natural products as inspiration for the development of bacterial antibiofilm agents
Natural products have historically been a rich source of diverse chemical matter with
numerous biological activities, and have played an important role in drug discovery in many …
numerous biological activities, and have played an important role in drug discovery in many …
Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance
B Parrino, D Schillaci, I Carnevale, E Giovannetti… - European journal of …, 2019 - Elsevier
Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …
is currently considered a key virulence factor for pathogens responsible for serious chronic …
Small molecule control of bacterial biofilms
RJ Worthington, JJ Richards… - Organic & biomolecular …, 2012 - pubs.rsc.org
Bacterial biofilms are defined as a surface attached community of bacteria embedded in a
matrix of extracellular polymeric substances that they have produced. When in the biofilm …
matrix of extracellular polymeric substances that they have produced. When in the biofilm …
Antimicrobial effects of sulfonyl derivative of 2 (5 H)-furanone against planktonic and biofilm associated methicillin-resistant and-susceptible Staphylococcus aureus
The gram-positive opportunistic bacterium Staphylococcus aureus is one of the most
common causatives of a variety of diseases including skin and skin structure infection or …
common causatives of a variety of diseases including skin and skin structure infection or …
Palladium‐Catalyzed Asymmetric C(sp3)−H Allylation of 2‐Alkylpyridines
R Murakami, K Sano, T Iwai, T Taniguchi… - Angewandte …, 2018 - Wiley Online Library
The palladium‐catalyzed asymmetric side‐chain C (α)‐allylation of 2‐alkylpyridines, without
using an external base, was developed. The high linear selectivities and enantioselectivities …
using an external base, was developed. The high linear selectivities and enantioselectivities …
Current and future approaches to the prevention and treatment of staphylococcal medical device-related infections
S Hogan, NT Stevens, H Humphreys… - Current …, 2015 - ingentaconnect.com
Staphylococci, in particular Staphylococcus aureus and Staphylococcus epidermidis, are a
leading cause of healthcareassociated infections. Patients who have a medical device …
leading cause of healthcareassociated infections. Patients who have a medical device …
Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE)
A AbdelKhalek, NS Abutaleb, H Mohammad… - PloS one, 2018 - journals.plos.org
Enterococci represent one of the microbial world's most challenging enigmas. Colonization
of the gastrointestinal tract (GIT) of high-risk/immunocompromised patients by enterococci …
of the gastrointestinal tract (GIT) of high-risk/immunocompromised patients by enterococci …
Synthesis and biological evaluation of novel indole-derived thioureas
G Sanna, S Madeddu, G Giliberti, S Piras, M Struga… - Molecules, 2018 - mdpi.com
A series of 2-(1 H-indol-3-yl) ethylthiourea derivatives were prepared by condensation of 2-
(1 H-indol-3-yl) ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media …
(1 H-indol-3-yl) ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media …
Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms
C Bunders, J Cavanagh, C Melander - Organic & biomolecular …, 2011 - pubs.rsc.org
Anti-biofilm agents have been developed based upon the flustramine family of alkaloids
isolated from Flustra foliacea. A Garg interrupted Fischer indolization reaction was employed …
isolated from Flustra foliacea. A Garg interrupted Fischer indolization reaction was employed …