The joint analysis of the genome, epigenome, transcriptome, proteome and/or metabolome
from single cells is transforming our understanding of cell biology in health and disease. In …

Visualization of the cellular heterogeneity and spatial architecture of the tumor
microenvironment (TME) is becoming increasingly important to understand mechanisms of …

Mapping tumor metabolic remodeling and their spatial crosstalk with surrounding non-tumor
cells can fundamentally improve our understanding of tumor biology, facilitates the …

Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

Metabolic reprogramming in cancer and immune cells occurs to support their increasing
energy needs in biological tissues. Here we propose Single Cell Spatially resolved …

Spatial metabolomics is an emerging field of omics research that has enabled localizing
small molecules in tissues and cells. Mass spectrometry imaging (MSI) technologies allow …

Small molecule tyrosine kinase inhibitors (TKIs) are widely used as anticancer drugs
approved by US FDA. However, the toxicities of TKIs to multiple organs have greatly limited …

Spatial omics has emerged as a rapidly growing and fruitful field with hundreds of
publications presenting novel methods for obtaining spatially resolved information for any …

Without insight into the correlation between the structure and properties, anion exchange
membranes (AEMs) for fuel cells are developed usually using the empirical trial and error …

Innate lymphoid cells (ILCs) are a family of predominantly tissue-resident lymphocytes that
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …