Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …

Tumor-associated macrophages (TAMs) constitute the most prolific resident of the tumor
microenvironment (TME) that regulate its TME into tumor suppressive or progressive milieu …

Objective Identify the prognostic value and investigate the association between programmed
cell death 1 (PDCD1) gene expression and immune infiltration in pan-cancer. Methods We …

Immune checkpoint inhibitors (ICIs) are a group of drugs employed in the treatment of
various types of malignant tumors and improve the therapeutic effect. ICIs blocks negative co …

The programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) immune
checkpoint proteins hold promise as diagnostic, prognostic, and therapeutic targets for …

Simple Summary Cancer heterogeneity, which occurs in most cancer patients, has been
known and studied by experienced pathologists since the early 19th century. Intratumoral …

The new immunotherapy targeting the programmed cell death 1 (PD-1) receptor and its
cognate ligand PD-L1 has renewed hopes of eradicating the most difficult human cancers to …

Anaplastic thyroid cancer (ATC) is one of the worst human malignancies, with an associated
median survival of only 5 months. It is resistant to conventional thyroid cancer therapies …

Amongst the chief targets of immune-checkpoint inhibitors (ICIs), namely the Programmed
cell death protein 1 (PD-1)/PD-Ligands (Ls) axis, most research has focused on PD-L1 …

Anaplastic thyroid carcinoma (ATC) is a rare and aggressive form of thyroid carcinoma (TC).
Currently, there are no effective treatments for this condition. In the past few years, targeted …