The blood-brain barrier (BBB) protects the central nervous system (CNS) by restricting the
passage of molecules and microorganisms. Despite this barrier, however, the fungal …

Cryptococcus neoformans (Cn) is an opportunistic, encapsulated, yeast-like fungus that
causes severe meningoencephalitis, especially in countries with high HIV prevalence. In …

Cryptococcal meningoencephalitis is a fungal infection that predominantly affects
immunocompromised patients and is uniformly fatal if left untreated. Timely diagnosis is …

Cryptococcus neoformans is the main etiologic agent of cryptococcal meningitis and causes
a significant number of deadly infections per year. Although it is well appreciated that host …

Fungal pathogens are underappreciated causes of significant morbidity and mortality
worldwide. In previous studies, we determined that a heat-killed, Cryptococcus neoformans …

Cryptococcus gattii is an etiologic agent of cryptococcosis, a potentially fatal disease that
affects humans and animals. The successful infection of mammalian hosts by cryptococcal …

Cryptococcus neoformans, an AIDS-defining opportunistic pathogen, is the leading cause of
fungal meningitis worldwide and is responsible for hundreds of thousands of deaths …

Cryptococcus is a ubiquitous environmental fungus and frequent colonizer of human lungs.
Colonization can lead to diverse outcomes, from clearance to long-term colonization to life …

Pathogens must compete with hosts to acquire sufficient iron for proliferation during
pathogenesis. The pathogenic fungus Cryptococcus neoformans is capable of acquiring iron …

The genus Cryptococcus includes several species pathogenic for humans. Until recently, the
two major pathogenic species were recognized to be Cryptococcus neoformans and …