Mitochondrial mutations and mitoepigenetics: Focus on regulation of oxidative stress-induced responses in breast cancers
K Chen, P Lu, NM Beeraka, OA Sukocheva… - Seminars in cancer …, 2022 - Elsevier
Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-developing
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …
Mitochondrial DNA methylation and human diseases
A Stoccoro, F Coppedè - International Journal of Molecular Sciences, 2021 - mdpi.com
Epigenetic modifications of the nuclear genome, including DNA methylation, histone
modifications and non-coding RNA post-transcriptional regulation, are increasingly being …
modifications and non-coding RNA post-transcriptional regulation, are increasingly being …
Mitochondria, cholesterol and cancer cell metabolism
V Ribas, C García-Ruiz… - Clinical and translational …, 2016 - Springer
Given the role of mitochondria in oxygen consumption, metabolism and cell death
regulation, alterations in mitochondrial function or dysregulation of cell death pathways …
regulation, alterations in mitochondrial function or dysregulation of cell death pathways …
The landscape of mtDNA modifications in cancer: a tale of two cities
KL Hertweck, S Dasgupta - Frontiers in oncology, 2017 - frontiersin.org
Mitochondria from normal and cancerous cells represent a tale of two cities, wherein both
execute similar processes but with different cellular and molecular effects. Given the number …
execute similar processes but with different cellular and molecular effects. Given the number …
Mitoepigenetics and its emerging roles in cancer
Z Dong, L Pu, H Cui - Frontiers in cell and developmental biology, 2020 - frontiersin.org
In human beings, there is a∼ 16,569 bp circular mitochondrial DNA (mtDNA) encoding 22
tRNAs, 12S and 16S rRNAs, 13 polypeptides that constitute the central core of ETC/OxPhos …
tRNAs, 12S and 16S rRNAs, 13 polypeptides that constitute the central core of ETC/OxPhos …
Platelet mitochondrial DNA methylation predicts future cardiovascular outcome in adults with overweight and obesity
S Corsi, S Iodice, L Vigna, A Cayir, JC Mathers… - Clinical …, 2020 - Springer
Background The association between obesity and cardiovascular disease (CVD) is proven,
but why some adults with obesity develop CVD while others remain disease-free is poorly …
but why some adults with obesity develop CVD while others remain disease-free is poorly …
Increase in mitochondrial D-loop region methylation levels in mild cognitive impairment individuals
A Stoccoro, F Baldacci, R Ceravolo… - International Journal of …, 2022 - mdpi.com
Methylation levels of the mitochondrial displacement loop (D-loop) region have been
reported to be altered in the brain and blood of Alzheimer's disease (AD) patients. Moreover …
reported to be altered in the brain and blood of Alzheimer's disease (AD) patients. Moreover …
Mitochondrial health, the epigenome and healthspan
MA Aon, S Cortassa, M Juhaszova, SJ Sollott - Clinical Science, 2016 - portlandpress.com
Food nutrients and metabolic supply–demand dynamics constitute environmental factors
that interact with our genome influencing health and disease states. These gene …
that interact with our genome influencing health and disease states. These gene …
Hypermethylation of mitochondrial cytochrome b and cytochrome c oxidase II genes with decreased mitochondrial DNA copy numbers in the APP/PS1 transgenic …
Y Xu, L Cheng, J Sun, F Li, X Liu, Y Wei, M Han… - Neurochemical …, 2021 - Springer
Alzheimer's disease (AD) is the most common cause of dementia. Increasing evidence
shows that mitochondrial DNA (mtDNA) methylation plays an essential role in many …
shows that mitochondrial DNA (mtDNA) methylation plays an essential role in many …
Mitochondrial DNA and neurodegeneration: any role for dietary antioxidants?
L Bordoni, R Gabbianelli - Antioxidants, 2020 - mdpi.com
The maintenance of the mitochondrial function is essential in preventing and counteracting
neurodegeneration. In particular, mitochondria of neuronal cells play a pivotal role in …
neurodegeneration. In particular, mitochondria of neuronal cells play a pivotal role in …