Associations between genetic variation and traits are often in noncoding regions with strong
linkage disequilibrium (LD), where a single causal variant is assumed to underlie the …

To further our understanding of inherited susceptibility to Hodgkin lymphoma (HL), we
performed a meta-analysis of 7 genome-wide association studies totaling 5325 HL cases …

HIV-1-infected infants develop broadly neutralizing antibodies (bnAbs) more rapidly than
adults, suggesting differences in the neonatal versus adult responses to the HIV-1 envelope …

Introduction Steroid-sensitive nephrotic syndrome (SSNS) is the most common form of
kidney disease in children worldwide. Genome-wide association studies (GWAS) have …

Genetic diseases can be classified along a spectrum based on the number of genes and
genetic variants involved in their development. On one end of the spectrum are Mendelian …

Abstract Treatment of BCR-ABL1⁺ human leukemia, especially for early phase chronic
myeloid leukemia (CML) patients, has been greatly improved by ABL tyrosine kinase …

Idiopathic nephrotic syndrome (INS) is classified in children according to response to initial
corticosteroid therapy into steroid sensitive (SSNS) and steroid resistant nephrotic syndrome …

Human genetics connects natural genetic variation with molecular and organism
phenotypes, yet the space of human genetic variation is vast and almost entirely non-coding …

To further our understanding of inherited susceptibility to Hodgkin lymphoma (HL), we
performed a meta-analysis of seven genome-wide association studies totalling 5,325 HL …

Joubert syndrome (JBTS) is a predominantly autosomal recessive neurodevelopmental
disorder that presents with characteristic malformations of the cerebellar vermis, superior …