[HTML][HTML] Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Rolling circle amplification (RCA)-based DNA hydrogel

C Yao, R Zhang, J Tang, D Yang - Nature protocols, 2021 - nature.com
DNA hydrogels have unique properties, including sequence programmability, precise
molecular recognition, stimuli-responsiveness, biocompatibility and biodegradability, that …

[HTML][HTML] DNA nanostructure-based nucleic acid probes: construction and biological applications

DX Wang, J Wang, YX Wang, YC Du, Y Huang… - Chemical …, 2021 - pubs.rsc.org
In recent years, DNA has been widely noted as a kind of material that can be used to
construct building blocks for biosensing, in vivo imaging, drug development, and disease …

Rational design of dna hydrogels based on molecular dynamics of polymers

Y Li, R Chen, B Zhou, Y Dong, D Liu - Advanced Materials, 2024 - Wiley Online Library
In recent years, DNA has emerged as a fascinating building material to engineer hydrogel
due to its excellent programmability, which has gained considerable attention in biomedical …

Hydrogel nanoarchitectonics: an evolving paradigm for ultrasensitive biosensing

ZS Nishat, T Hossain, MN Islam, HP Phan, MA Wahab… - Small, 2022 - Wiley Online Library
The integration of nanoarchitectonics and hydrogel into conventional biosensing platforms
offers the opportunities to design physically and chemically controlled and optimized soft …

[HTML][HTML] The compact integration of a cascaded HCR circuit for highly reliable cancer cell discrimination

P Dong, R Li, S He, Q Zhang, J Shang, Y Jiang… - Chemical …, 2023 - pubs.rsc.org
The accurate identification of multiple biomarkers involved in disease plays a vital role in
effectively distinguishing cancer cells from normal cells, facilitating reliable cancer …

The recent development of hybridization chain reaction strategies in biosensors

C Zhang, J Chen, R Sun, Z Huang, Z Luo, C Zhou… - ACS …, 2020 - ACS Publications
With the continuous development of biosensors, researchers have focused increasing
attention on various signal amplification strategies to pursue superior performance for more …

A temporally resolved DNA framework state machine in living cells

Y Zhao, S Cao, Y Wang, F Li, L Lin, L Guo… - Nature Machine …, 2023 - nature.com
The environments in living cells are highly heterogeneous and compartmentalized, posing a
grand challenge for the deployment of theranostic agents with spatiotemporal precision …

Reconfigurable A-motif, i-motif and triplex nucleic acids for smart pH-responsive DNA hydrogels

Y Hu, JY Ying - Materials Today, 2023 - Elsevier
Integrating dynamic reconfigurable DNA crosslinking units, smart DNA hydrogels have
demonstrated sol–gel transition, shape memory, self-healing, sensing, cargo encapsulation …

Fast Transport and Transformation of Biomacromolecular Substances via Thermo‐Stimulated Active “Inhalation–Exhalation” Cycles of Hierarchically Structured Smart …

X Du, PP He, C Wang, X Wang, Y Mu… - Advanced …, 2023 - Wiley Online Library
Although smart hydrogels hold great promise in biosensing and biomedical applications,
their response to external stimuli is governed by the passive diffusion‐dependent substance …