Progress and challenges for malaria vaccines

TL Richie, A Saul - Nature, 2002 - nature.com
Malaria causes much physical and economic hardship in tropical regions, particularly in
communities where medical care is rudimentary. Should a vaccine be developed, it is the …

Plasmodium vivax: who cares?

MR Galinski, JW Barnwell - Malaria journal, 2008 - Springer
More attention is being focused on malaria today than any time since the world's last efforts
to achieve eradication over 40 years ago. The global community is now discussing …

Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein

BT Grimberg, R Udomsangpetch, J Xainli… - PLoS …, 2007 - journals.plos.org
Background Plasmodium vivax invasion requires interaction between the human Duffy
antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) …

Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC)

H Choe, MJ Moore, CM Owens, PL Wright… - Molecular …, 2005 - Wiley Online Library
Plasmodium vivax is one of four Plasmodium species that cause human malaria. P. vivax
and a related simian malaria parasite, Plasmodium knowlesi, invade erythrocytes by binding …

Conserved residues in the Plasmodium vivax Duffy-binding protein ligand domain are critical for erythrocyte receptor recognition

KM VanBuskirk, E Sevova… - Proceedings of the …, 2004 - National Acad Sciences
Malaria merozoite invasion of human erythrocytes depends on recognition of specific
erythrocyte surface receptors by parasite ligands. Plasmodium vivax merozoite invasion is …

PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

FJ Martinez, M White, M Guillotte-Blisnick, C Huon… - npj Vaccines, 2024 - nature.com
The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein
(PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate invasion. A …

Progress towards the development of a P. vivax vaccine

SL De, FB Ntumngia, J Nicholas… - Expert review of …, 2021 - Taylor & Francis
Introduction Plasmodium vivax causes significant public health problems in endemic
regions. A vaccine to prevent disease is critical, considering the rapid spread of drug …

A novel erythrocyte binding protein of Plasmodium vivax suggests an alternate invasion pathway into Duffy-positive reticulocytes

FB Ntumngia, R Thomson-Luque, LM Torres… - MBio, 2016 - Am Soc Microbiol
Erythrocyte invasion by malaria parasites is essential for blood-stage development and an
important determinant of host range. In Plasmodium vivax, the interaction between the Duffy …

Bacterially expressed and refolded receptor binding domain of Plasmodium falciparum EBA-175 elicits invasion inhibitory antibodies

KC Pandey, S Singh, P Pattnaik, CR Pillai… - Molecular and …, 2002 - Elsevier
Malaria parasites make specific receptor–ligand interactions to invade erythrocytes. A 175
kDa Plasmodium falciparum erythrocyte binding antigen (EBA-175) binds sialic acid …

Mapping binding residues in the Plasmodium vivax domain that binds Duffy antigen during red cell invasion

D Hans, P Pattnaik, A Bhattacharyya… - Molecular …, 2005 - Wiley Online Library
Plasmodium vivax depends on interaction with the Duffy antigen/receptor for chemokines
(DARC) for invasion of human erythrocytes. The 140 kDa P. vivax Duffy‐binding protein …