SUMMARY The PhoP/PhoQ two-component system governs virulence, Mg2+ homeostasis,
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …

We have developed a general profile for the proteins of the TetR family of repressors. The
stretch that best defines the profile of this family is made up of 47 amino acid residues that …

Innate immune receptors recognize microorganism-specific motifs. One such receptor–
ligand complex is formed between the mammalian Toll-like receptor 4 (TLR4)–MD2–CD14 …

PhoQ is a membrane bound sensor kinase important for the pathogenesis of a number of
Gram-negative bacterial species. PhoQ and its cognate response regulator PhoP constitute …

Pseudomonas aeruginosa causes serious nosocomial infections, and an important
virulence factor produced by this organism is lipopolysaccharide (LPS). This review …

Antimicrobial peptides (AMPs) are ribosomally synthesized natural antibiotics that are
crucial effectors of innate immune systems in all living organisms. AMPs are diverse …

Photorhabdus and Xenorhabdus bacteria colonize the intestines of the infective soil‐
dwelling stage of entomophagous nematodes, Heterorhabditis and Steinernema …

Recent genetic and molecular analyses have revealed how several strategies enable
bacteria to persist and overcome insect immune defences. Genetic and genomic tools that …

The PhoQ/PhoP signaling system responds to low magnesium and the presence of certain
cationic antimicrobial peptides. It regulates genes important for growth under these …

Members of the genus Xenorhabdus are entomopathogenic bacteria that associate with
nematodes. The nematode-bacteria pair infects and kills insects, with both partners …