The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

The development of reliable biosensing platforms plays a key role in the detection of
proteins in clinically and environmentally derived samples for diagnostics, as well as for …

A critical challenge in surface-based biomolecular detection is the reduced accessibility of
target molecules to probes arranged on a heterogeneous surface compared to probe–target …

The sensitivity of aptamer-based electrochemical sensors is often limited by restricted target
accessibility and surface-induced perturbation of the aptamer structure, which arise from …

MicroRNAs (miRNAs) have been identified as promising cancer biomarkers due to their
stable presence in serum. As an alternative to PCR-based homogenous assays, surface …

MicroRNAs (miRNAs) play important roles as significant biomarkers in disease diagnostics.
Here, an electrochemical biosensor was developed for the quick, sensitive, and specific …

Biosensors represent biomimetic analytical tools for addressing increasing needs in medical
diagnosis, environmental monitoring, security, and biodefense. Nevertheless, widespread …

In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Design and development of surface-based biosensors is challenging given the
multidisciplinary nature of this enterprise, which is certainly the case for electrochemical …

Specific and predictable hybridization of the polynucleotide sequences to their
complementary counterparts plays a fundamental role in the rational design of new nucleic …