Research progress on small molecule inhibitors targeting KRAS G12C with acrylamide structure and the strategies for solving KRAS inhibitor resistance
Z Jiang, Y Li, X Zhou, J Wen, P Zheng, W Zhu - Bioorganic & Medicinal …, 2024 - Elsevier
KRAS (Kirsten-RAS) is a highly mutated gene in the RAS (rat sarcoma) gene family that acts
as a critical switch in intracellular signaling pathways, regulating cell proliferation …
as a critical switch in intracellular signaling pathways, regulating cell proliferation …
Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells
L Senggunprai, V Kukongviriyapan… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives Strategies that induce apoptosis of malignant cells are recognized as effective
cancer treatments. This study evaluated the apoptosis-inducing ability of momordin Ic …
cancer treatments. This study evaluated the apoptosis-inducing ability of momordin Ic …