Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

Autophagy causes the breakdown of damaged proteins and organelles to their constituent
components. The phosphatidylinositol 3‐kinase (PI3K) pathway played an important role in …

Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

Cancer formation is a complex and highly regulated multi-step process which is highly
dependent of its environment, from the tissue to the patient. This complexity implies the …

Background Treatment options for women presenting with triple negative breast cancer
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …

Cellular ROS production participates in various cellular functions but its accumulation
decides the cell fate. Malignant cells have higher levels of ROS and active antioxidant …

Metabolic adaptability is essential for tumor progression and includes cooperation between
cancer cells with different metabolic phenotypes. Optimal glucose supply to glycolytic cancer …

Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Colorectal cancer (CRC) remains a leading cause of cancer death in both men and women
worldwide. Among the factors and mechanisms that are involved in the multifactorial etiology …

The global incidence of cancer and cancer‐related mortality is expected to rise in recent
years despite advancements in cancer diagnosis and therapeutics. Increasing evidences of …