Drosophila melanogaster provides an important resource for in vivo modifier screens of
neurodegenerative diseases. To study the underlying pathogenesis of Alzheimer's disease …

Neurodegenerative diseases (NDs) are a heterogeneous group of aging-associated
ailments characterized by interrupting cellular proteostasic machinery and the misfolding of …

Alzheimer's disease (AD) is the most frequent cause of dementia. After decades of research,
we know the importance of the accumulation of protein aggregates such as β-amyloid …

Tauopathies are devastating and ultimately fatal neurodegenerative diseases, which are
histopathologically defined by insoluble filamentous deposits of abnormally phosphorylated …

Humans spend nearly a third of their life sleeping, yet, despite decades of research the
function of sleep still remains a mystery. Sleep has been linked with various biological …

Alzheimer's disorder is one of the most common worldwide health problems, and its
prevalence continues to increase, thereby straining the healthcare budgets of both …

Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by
memory loss and decreased synaptic function. Advances in transgenic animal models of AD …

Currently, all the existing treatments for Alzheimer's disease (AD) fail to stall progression due
to longer duration of time between onset of the symptoms and diagnosis of the disease …

To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's
disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein …

Alzheimer disease (AD) is one of the main causes of age-related dementia and
neurodegeneration. However, the onset of the disease and the mechanisms causing …