Energy and information flows in autonomous systems

J Ehrich, DA Sivak - Frontiers in Physics, 2023 - frontiersin.org
Multi-component molecular machines are ubiquitous in biology. We review recent progress
on describing their thermodynamic properties using autonomous bipartite Markovian …

Dynamic and thermodynamic bounds for collective motor-driven transport

MP Leighton, DA Sivak - Physical Review Letters, 2022 - APS
Molecular motors work collectively to transport cargo within cells, with anywhere from one to
several hundred motors towing a single cargo. For a broad class of collective-transport …

Performance scaling and trade-offs for collective motor-driven transport

MP Leighton, DA Sivak - New Journal of Physics, 2022 - iopscience.iop.org
Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a
highly collective process. An individual cargo is often pulled by a team of transport motors …

Cooperation and competition in the collective drive by motor proteins: mean active force, fluctuations, and self-load

C Karan, D Chaudhuri - Soft Matter, 2023 - pubs.rsc.org
We consider the dynamics of a bio-filament under the collective drive of motor proteins. They
are attached irreversibly to a substrate and undergo stochastic attachment–detachment with …

Dynamics of cooperative cargo transport by two elastically coupled kinesin motors

YB Fu, SK Guo, PY Wang, P Xie - The European Physical Journal E, 2019 - Springer
Intracellular transport is performed often by multiple motor proteins bound to the same cargo.
Here, we study theoretically collective transport of the cargo by two kinesin motors. We …

Frictional drag produced by motor proteins during cargo transport

U Nakul, M Gopalakrishnan - Europhysics Letters, 2021 - iopscience.iop.org
When transporting cellular cargoes along the cytoskeletal filament track, motor proteins
produce additional frictional drag. This" protein friction" determines the mean speed of a …

Effects of rebinding rate and asymmetry in unbinding rate on cargo transport by multiple kinesin motors

Y Wang, YY Liu, J Liang, PY Wang… - … in Theoretical Physics, 2021 - iopscience.iop.org
Many intracellular transports are performed by multiple molecular motors in a cooperative
manner. Here, we use stochastic simulations to study the cooperative transport by multiple …

Cooperative dynamics of coupled motor–cargoes system with stochastic interactions in the crowded environment

L Lin, Y Lu, L Yu, H Wang - Chinese Journal of Physics, 2021 - Elsevier
In this study, we investigate the cooperative transport behaviors of coupled motor–cargoes
system, in which multiple passive cargoes stochastically interact with one active Brownian …