Background Anti-cancer therapy is often a cause of premature ovarian insufficiency and
infertility since the ovarian follicle reserve is extremely sensitive to the effects of …

Anti-Müllerian hormone (AMH), also called Müllerian inhibiting substance, was shown to be
synthesized by the ovary in the 1980s. This article reviews the main findings of the past 20 …

Cancer treatments are increasingly effective, but can result in iatrogenic premature ovarian
insufficiency. Ovarian tissue cryopreservation is the only option available to preserve fertility …

Purpose In this review, the current knowledge on anti-Müllerian hormone (AMH) is
presented, concerning its value in disease and IVF treatment as well as in terms of its …

Adjuvant gonadotropin‐releasing hormone analogues for the prevention of chemotherapy‐induced
premature ovarian failure in premenopausal women - Chen, H - 2019 | Cochrane Library Skip …

Primary ovarian insufficiency (POI) is an uncommon yet devastating occurrence that results
from a premature depletion of the ovarian pool of primordial follicles. Our understanding of …

The follicular ovarian reserve, constituted by primordial follicles (PMFs), is established early
in life, then keeps declining regularly along reproductive life. The maintenance of a normal …

BACKGROUND Fertility loss during female ageing is associated with increasing basal FSH
and decreasing anti-Müllerian hormone (AMH) concentrations, together with compromised …

It is well established that DNA-damaging chemotherapies can cause infertility and ovarian
endocrine failure by depleting the ovarian reserve of primordial follicles. Currently, no …

Cancer therapy can cause off-target effects including ovarian damage, which may result in
primary ovarian insufficiency in girls and premenopausal women. Loss of ovarian follicles …