Organoiridium complexes: anticancer agents and catalysts

Z Liu, PJ Sadler - Accounts of Chemical Research, 2014 - ACS Publications
Conspectus Iridium is a relatively rare precious heavy metal, only slightly less dense than
osmium. Researchers have long recognized the catalytic properties of square-planar IrI …

Bioactive luminescent transition‐metal complexes for biomedical applications

DL Ma, HZ He, KH Leung, DSH Chan… - Angewandte Chemie …, 2013 - Wiley Online Library
The serendipitous discovery of the anticancer drug cisplatin cemented medicinal inorganic
chemistry as an independent discipline in the 1960s. Luminescent metal complexes have …

Coordination-based circularly polarized luminescence emitters: Design strategy and application in sensing

J Gong, X Zhang - Coordination Chemistry Reviews, 2022 - Elsevier
Chiral systems emitting circularly polarized luminescence (CPL) have great potential in
practical applications including but not limiting to 3D optical displays, information storage …

Group 9 organometallic compounds for therapeutic and bioanalytical applications

DL Ma, DSH Chan, CH Leung - Accounts of chemical research, 2014 - ACS Publications
Conspectus Compared with organic small molecules, metal complexes offer several distinct
advantages as therapeutic agents or biomolecular probes. Carbon atoms are typically …

Recent developments in G-quadruplex probes

DL Ma, Z Zhang, M Wang, L Lu, HJ Zhong… - Chemistry & Biology, 2015 - cell.com
Accumulating evidence has linked G-quadruplex structures to a number of biological
processes in vivo, including DNA replication, transcription, and genomic maintenance …

Fabricating MnO2 Nanozymes as Intracellular Catalytic DNA Circuit Generators for Versatile Imaging of Base‐Excision Repair in Living Cells

F Chen, M Bai, K Cao, Y Zhao, J Wei… - Advanced Functional …, 2017 - Wiley Online Library
Nanomaterial/DNA integrated systems have become an emerging tool for intracellular
imaging. However, intracellular catalytic DNA circuit is rarely explored. Commonly used …

Synthesis, labeling and bioanalytical applications of a tris (2, 2′-bipyridyl) ruthenium (II)-based electrochemiluminescence probe

X Zhou, D Zhu, Y Liao, W Liu, H Liu, Z Ma, D Xing - nature protocols, 2014 - nature.com
Assays using probes labeled with electrochemiluminescent moieties are extremely powerful
analytical tools that are used in fields such as medical diagnostics, environmental analysis …

Recent developments on optical and electrochemical sensing of copper (II) ion based on transition metal complexes

A Ramdass, V Sathish, E Babu, M Velayudham… - Coordination Chemistry …, 2017 - Elsevier
Abstract Copper (II), Cu 2+, ion plays not only a fundamental role to sustain important
physiological processes in living organisms, but also an important environmental pollutant …

Excision repair-initiated enzyme-assisted bicyclic cascade signal amplification for ultrasensitive detection of uracil-DNA glycosylase

L Wang, M Ren, Q Zhang, B Tang, C Zhang - Analytical chemistry, 2017 - ACS Publications
Uracil-DNA glycosylase (UDG) is an important base excision repair (BER) enzyme
responsible for the repair of uracil-induced DNA lesion and the maintenance of genomic …

Coupling photoelectrochemical and electrochemical strategies in one probe electrode: Toward sensitive and reliable dual-signal bioassay for uracil-DNA glycosylase …

Y Lu, H Zhao, GC Fan, X Luo - Biosensors and Bioelectronics, 2019 - Elsevier
Uracil-DNA glycosylase (UDG) is a typical initiator for base excision repair (BER) process.
Since aberrant expression of UDG is relevant to a variety of cancers, analysis of UDG activity …