Design, Synthesis, and Biological Evaluation of Ferulic Acid-Piperazine Derivatives Targeting Pathological Hallmarks of Alzheimer's Disease
Alzheimer's disease (AD) is the most prevalent cause of dementia and is characterized by
low levels of acetyl and butyrylcholine, increased oxidative stress, inflammation …
low levels of acetyl and butyrylcholine, increased oxidative stress, inflammation …
Rethinking common solvents in butyrylcholinesterase activity assays
Cholinesterases are a group of enzymes that prevent the message of the neurotransmitter
acetylcholine from being transmitted in an undesirable manner. The primary classes of this …
acetylcholine from being transmitted in an undesirable manner. The primary classes of this …
[HTML][HTML] Novel Organoruthenium (II) Complex C1 Selectively Inhibits Butyrylcholinesterase without Side Effects on Neuromuscular Transmission
T Trobec, MC Žužek, K Sepčić, J Kladnik… - International journal of …, 2023 - mdpi.com
Enzyme butyrylcholinesterase (BChE) shows increased activity in some brain regions after
progression of Alzheimer's disease and is therefore one of the therapeutic targets for …
progression of Alzheimer's disease and is therefore one of the therapeutic targets for …
[HTML][HTML] Kinetics and computational study of butyrylcholinesterase inhibition by methylrosmarinate: relevance to Alzheimer's disease treatment
Butyrylcholinesterase (BChE) performs a significant function in Alzheimer's disease
progression. Experimental studies have shown that the function of BChE in the attenuation …
progression. Experimental studies have shown that the function of BChE in the attenuation …
The Inhibition of Glutathione S-Transferases and Butyrylcholinesterase by Antidepressants: A Mini-Review on Enzyme-Drug Interactions
Background: Compromises in the cellular enzymatic defense barrier can increase the
duration of exposure to electrophiles and the severity of toxicity they may incur. Objective: In …
duration of exposure to electrophiles and the severity of toxicity they may incur. Objective: In …