The problem of wound healing in diabetes—from molecular pathways to the design of an animal model

M Mieczkowski, B Mrozikiewicz-Rakowska… - International journal of …, 2022 - mdpi.com
Chronic wounds are becoming an increasingly common clinical problem due to an aging
population and an increased incidence of diabetes, atherosclerosis, and venous …

The regulatory role of miRNA and lncRNA on autophagy in diabetic nephropathy

S Yu, Y Li, X Lu, Z Han, C Li, X Yuan, D Guo - Cellular Signalling, 2024 - Elsevier
Diabetic nephropathy (DN) is a serious complication of diabetes that causes glomerular
sclerosis and end-stage renal disease, leading to ascending morbidity and mortality in …

Piceatannol promotes neuroprotection by inducing mitophagy and mitobiogenesis in the experimental diabetic peripheral neuropathy and hyperglycemia-induced …

I Khan, K Preeti, R Kumar, DK Khatri… - International …, 2023 - Elsevier
Abstract Piceatannol (PCN), a SIRT1 activator, regulates multiple oxidative stress
mechanism and has anti-inflammatory potential in various inflammatory conditions …

Current updates on metabolites and its interlinked pathways as biomarkers for diabetic kidney disease: a systematic review

S Das, D Rajeswari, G Venkataraman, R Elumalai… - Translational …, 2023 - Elsevier
Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus
(DM) that poses a serious risk as it can lead to end-stage renal disease (ESRD). DKD is …

Activation of SIRT1 by silibinin improved mitochondrial health and alleviated the oxidative damage in experimental diabetic neuropathy and high glucose-mediated …

I Khan, K Preeti, R Kumar, DK Khatri… - Archives of Physiology …, 2024 - Taylor & Francis
Background Silibinin (SBN), a sirtuin 1 (SIRT1) activator, has been evaluated for its anti-
inflammatory activity in many inflammatory diseases. However, its role in diabetes-induced …

Ultra‐high performance liquid chromatography coupled to tandem mass spectrometry‐based metabolomics study of diabetic distal symmetric polyneuropathy

J Xu, Q Chen, M Cai, X Han, H Lu - Journal of Diabetes …, 2023 - Wiley Online Library
Abstract Aims/Introduction Distal symmetric polyneuropathy (DSPN) is a common
complication of type 2 diabetes mellitus, but the underlining mechanisms have not yet been …

Current advancement in the preclinical models used for the assessment of diabetic neuropathy

T Saini, PM Mazumder - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Diabetic neuropathy is one of the prevalent and debilitating microvascular complications of
diabetes mellitus, affecting a significant portion of the global population. Relational …

Protective effects of GuanXinNing tablet (GXNT) on diabetic encephalopathy in zucker diabetic obesity (ZDF) rats

Y Li, J Chen, H Tu, Q Ma, M Wang, J Chen… - … Medicine and Therapies, 2023 - Springer
Background Diabetic encephalopathy (DE) is a complication of diabetes that leads to
cognitive and behavioral decline. Utilizing safe and effective complementary and alternative …

Chrysin improves diabetic nephropathy by regulating the AMPK‐mediated lipid metabolism in HFD/STZ‐induced DN mice

Y Zhou, H Tao, N Xu, S Zhou, Y Peng… - Journal of Food …, 2022 - Wiley Online Library
Diabetic nephropathy (DN) is a highly prevalent and severe diabetic complication. It is
urgent to explore high efficiency and minor side effects therapy for DN. Chrysin is a natural …

Pharmacological evaluation of Thuja occidentalis for the attenuation of neuropathy via AGEs and TNF-α inhibition in diabetic neuropathic rats

SK Bhargava, TG Singh, A Mannan, S Singh… - … Science and Pollution …, 2022 - Springer
When diabetes neuropathy occurs, the oxidative stress caused by chronic hyperglycemia
may result in chronic neuronal damage. To mitigate the effects of hyperglycemia-induced …