Dopamine is an important regulator of systemic blood pressure via multiple mechanisms. It
affects fluid and electrolyte balance by its actions on renal hemodynamics and epithelial ion …

Parkinson's disease (PD) is a chronic progressive neurological disorder characterized by
resting tremor, rigidity, bradykinesia, gait disturbance, and postural instability. Levodopa, the …

Levodopa (l-DOPA) is the naturally occurring precursor amino acid for dopamine and the
main therapeutic agent for neurologic disorders due to dopamine depletion, such as …

Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. The
disease has a multifactorial etiology with both environmental and genetic factors involved …

Hypertension and salt sensitivity of blood pressure are two conditions the etiologies of which
are still elusive because of the complex influences of genes, environment, and behavior …

Parkinson's disease is the second-most common neurodegenerative disorder worldwide.
Besides deciphering the mechanisms that underlie the etiology of the disease, it is important …

Glyphosate is one of the most commonly used herbicides worldwide due to its broad
spectrum of activity and reported low toxicity to humans. Glyphosate has an amino acid-like …

The role of dopamine D1-like receptors (DR) in the regulation of renal Na+ transporters,
natriuresis, and blood pressure is well established. However, the involvement of the …

Dysregulated expression of L-type amino acid transporter 1 (LAT1), which transports large
neutral amino acids, is a characteristic of various human cancers and possibly offers a …

Over-expression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR
immortalized renal proximal tubular cells. Background Spontaneously hypertensive rats …