Cigarette smoke and inflammation: role in cerebral aneurysm formation and rupture

N Chalouhi, MS Ali, RM Starke… - Mediators of …, 2012 - Wiley Online Library
Smoking is an established risk factor for subarachnoid hemorrhage yet the underlying
mechanisms are largely unknown. Recent data has implicated a role of inflammation in the …

The relationship of cigarette smoking to peripheral arterial disease.

JT Lu, MA Creager - Reviews in cardiovascular medicine, 2004 - europepmc.org
Cigarette smoking is one of the most important risk factors for peripheral arterial disease
(PAD). Smoking increases the risk of PAD by several fold and is a more influential risk factor …

Effect of nicotine on vasoconstrictor and vasodilator responses in human skin vasculature

CE Black, N Huang, PC Neligan… - American Journal …, 2001 - journals.physiology.org
Our objective was to test the hypothesis that acute exposure of human skin vasculature to
nicotine may have deleterious effects on endothelial function. Vasoconstriction and …

Nitric oxide-mediated blood flow regulation as affected by smoking and nicotine

N Toda, H Toda - European journal of pharmacology, 2010 - Elsevier
Cigarette smoking is a major risk factor for atherosclerosis, cerebral and coronary vascular
diseases, hypertension, and diabetes mellitus. Chronic smoking impairs endothelial function …

Fetal and neonatal nicotine exposure differentially regulates vascular contractility in adult male and female offspring

DL Xiao, X Huang, J Lawrence, S Yang… - Journal of Pharmacology …, 2007 - ASPET
Epidemiologic studies suggest that prenatal exposure to maternal cigarette smoking is
associated with an increased risk of elevated blood pressure in postnatal life. The present …

Transdermal nicotine mimics the smoking‐induced endothelial dysfunction

M Sabha, JE Tanus‐Santos, JCY Toledo… - Clinical …, 2000 - Wiley Online Library
Background Cigarette smoking is a major risk factor for coronary artery disease and causes
endothelial dysfunction, perhaps by decreasing the availability of nitric oxide availability in …

Chronic Nicotine Alters NO Signaling of Ca2+ Channels in Cerebral Arterioles

V Gerzanich, F Zhang, GA West, JM Simard - Circulation research, 2001 - Am Heart Assoc
Smoking is a major health hazard with proven deleterious effects on the cerebral circulation,
including a decrease in cerebral blood flow and a high risk for stroke. To elucidate cellular …

Neurogenic and endothelial nitric oxide regulates blood circulation in lingual and other oral tissues

N Toda, K Ayajiki, T Okamura - Journal of cardiovascular …, 2012 - journals.lww.com
Blood flow in oral tissues, including the tongue, salivary glands, gingiva, dental pulp, and lip,
plays an important role in modulating the complex oral functions involved in food intake. Oral …

N-methyl-d-aspartate-induced vasodilation is mediated by endothelium-independent nitric oxide release in piglets

F Domoki, JV Perciaccante, K Shimizu… - American Journal …, 2002 - journals.physiology.org
N-methyl-d-aspartate (NMDA) elicits pial arteriolar dilation that has been associated with
neuronal nitric oxide (NO) production. However, endothelial factors or glial P-450 …

The Influence of Nicotine on Trophoblast-Derived Exosomes in a Mouse Model of Pathogenic Preeclampsia

A Kubo, K Matsubara, Y Matsubara, H Nakaoka… - International Journal of …, 2023 - mdpi.com
Preeclampsia (PE) is a serious complication of pregnancy with a pathogenesis that is not
fully understood, though it involves the impaired invasion of extravillous trophoblasts (EVTs) …