Fatigue crack propagation and fracture toughness of cortical bone are radiation dose‐dependent

DB Crocker, I Hoffman, JLW Carter… - Journal of …, 2023 - Wiley Online Library
Cortical bone allograft sterilized with a standard γ‐radiation dose of 25–35kGy has
demonstrated reduced static and cyclic fracture resistance compared with unirradiated bone …

Effect of gamma irradiation and supercritical carbon dioxide sterilization with Novakill™ or ethanol on the fracture toughness of cortical bone

M Shin, MH Pelletier, V Lovric… - … Research Part B …, 2024 - Wiley Online Library
Sterilization of structural bone allografts is a critical process prior to their clinical use in large
cortical bone defects. Gamma irradiation protocols are known to affect tissue integrity in a …

[HTML][HTML] Dose-dependent effects of gamma radiation sterilization on the collagen matrix of human cortical bone allograft and its influence on fatigue crack propagation …

DB Crocker, TM Hering, O Akkus, ME Oest… - Cell and Tissue …, 2024 - Springer
Fatigue crack propagation resistance and high-cycle S–N fatigue life of cortical bone
allograft tissue are both negatively impacted in a radiation dose-dependent manner from 0 …

Can the sterilization protocol be improved to enhance the healing of allograft tendons? An in vivo study in rabbit tendons

H Zhang, M Xu, Y Zhao, Z Li, B Han… - Clinical Orthopaedics …, 2022 - journals.lww.com
Background Peracetic acid and irradiation are common sterilization methods for allograft
tendons; however, under some conditions, both methods adversely affect the fiber …

Fracture Toughness of Human Cortical Bone Exposed to Clinically-Relevant Radiation Doses and Correlation to Raman Spectroscopic Biomarkers

IE Hoffman - 2022 - rave.ohiolink.edu
The principal objective of this study was to determine if the fracture toughness and work-to-
fracture are radiation dose-dependent in the 0 to 25 kGy range. The secondary objective of …

CORR Insights®: The High-cycle Fatigue Life of Cortical Bone Allografts Is Radiation Sterilization Dose-dependent: An In Vitro Study

WR Walsh - Clinical Orthopaedics and Related Research®, 2022 - journals.lww.com
Structural cortical bone allografts are widely used and provide surgeons with a means to
deal with complex clinical problems related to bone loss. Allograft tissues provided by tissue …