The role of testosterone, the androgen receptor, and hypothalamic-pituitary–gonadal axis in depression in ageing Men

RL Hauger, UG Saelzler, MS Pagadala… - Reviews in Endocrine …, 2022 - Springer
Considerable research has shown that testosterone regulates many physiological systems,
modulates clinical disorders, and contributes to health outcome. However, studies on the …

The risk of new onset dementia and/or Alzheimer disease among patients with prostate cancer treated with androgen deprivation therapy: a systematic review and …

R Sari Motlagh, F Quhal, K Mori, N Miura… - The Journal of …, 2021 - auajournals.org
Purpose: Androgen deprivation therapy is a standard therapy for some patients with
localized and almost all patients with metastatic prostate cancer. Although several clinical …

Lower serum testosterone concentrations are associated with a higher incidence of dementia in men: the UK Biobank prospective cohort study

RJ Marriott, K Murray, L Flicker… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction The association of testosterone concentrations with dementia risk remains
uncertain. We examined associations of serum testosterone and sex hormone–binding …

Androgen deprivation therapy and depression in the prostate cancer patients: review of risk and pharmacological management

A Alwhaibi, S Alsanea, B Almadi, J Al-Sabhan… - The Aging …, 2022 - Taylor & Francis
Purpose: Despite the effectiveness of androgen deprivation therapy in advanced prostate
cancer, serious neuropsychiatric consequences in androgen deprivation therapy (ADT) …

Androgen deprivation therapy exacerbates Alzheimer's-associated cognitive decline via increased brain immune cell infiltration

C Zhang, M Aida, S Saggu, H Yu, L Zhou… - Science …, 2024 - science.org
Androgen deprivation therapy (ADT) for prostate cancer is associated with an increased risk
of dementia, including Alzheimer's disease (AD). The mechanistic connection between ADT …

Androgen deprivation therapy for prostate cancer and neurocognitive disorders: a systematic review and meta-analysis

DE Hinojosa-Gonzalez, A Zafar, G Saffati… - Prostate Cancer and …, 2024 - nature.com
Background Prostate cancer is a prevalent disease that urgently needs to address its
treatment-related complications. By examining existing evidence on the association …

Reminiscence therapy-based care program serves as an optional nursing modality in alleviating anxiety and depression, improving quality of life in surgical prostate …

T Huang, H Su, S Zhang, Y Huang - International Urology and Nephrology, 2022 - Springer
Purpose Reminiscence therapy is reported to attenuate the psychological disorders in
cancer patients, such as colorectal and lung cancer patients. However, relevant report on …

Neuropsychiatric impact of androgen deprivation therapy in patients with prostate cancer: current evidence and recommendations for the clinician

AL Siebert, L Lapping-Carr, AK Morgans - European urology focus, 2020 - Elsevier
Neuropsychiatric Impact of Androgen Deprivation Therapy in Patients with Prostate Cancer:
Current Evidence and Recommendations for the Clinician - ScienceDirect Skip to main …

Outcomes for arthroplasties in military health: a retrospective analysis of direct versus purchased care

A Haag, S Hosein, S Lyon, M Labban, J Wun… - Military …, 2023 - academic.oup.com
ABSTRACT Introduction The Department of Defense is reforming the military health system
where surgeries are increasingly referred from military treatment facilities (MTFs) with direct …

Androgen deprivation therapy and the risk of dementia after treatment for prostate cancer

PE Lonergan, SL Washington III, JE Cowan… - Journal of …, 2022 - journals.lww.com
Purpose: The association between androgen deprivation therapy (ADT) and dementia in
men with prostate cancer remains inconclusive. We assessed the association between …