Cell death mechanism of organometallic ruthenium (II) and iridium (III) arene complexes on HepG2 and Vero cells
SB Kavukcu, HK Ensarioğlu, H Karabıyık… - ACS …, 2023 - ACS Publications
Due to side effects and toxicity associated with platinum-derived metal-based drugs,
extensive research has been conducted on ruthenium (Ru) complexes. We aim to …
extensive research has been conducted on ruthenium (Ru) complexes. We aim to …
Enhanced in vitro cytotoxicity and antitumor activity in vivo of iridium (III) complexes liposomes targeting endoplasmic reticulum and mitochondria
W Li, X Wu, H Liu, C Shi, Y Yuan, L Bai, X Liao… - Journal of Inorganic …, 2022 - Elsevier
In this paper, two new iridium (III) complexes [Ir (ppy) 2 (CBIP)](PF 6)(ppy= 2-phenylpyridine,
CBIP= 2-(4′-chloro-(1, 1′-biphenyl))-1H-imidazo [4, 5-f][1, 10] phenanthroline)(Ir1) and [Ir …
CBIP= 2-(4′-chloro-(1, 1′-biphenyl))-1H-imidazo [4, 5-f][1, 10] phenanthroline)(Ir1) and [Ir …
Synthesis and biological evaluation of zwitterionic half-sandwich Rhodium (III) and Ruthenium (II) organometallic complexes
L Guo, X Hu, Y Yang, W An, J Gao, Q Liu, Z Liu - Bioorganic Chemistry, 2021 - Elsevier
Herein we present the synthesis and characterization of a panel of structurally related
zwitterionic piano-stool rhodium (III) and ruthenium (II) complexes. The identities of these …
zwitterionic piano-stool rhodium (III) and ruthenium (II) complexes. The identities of these …
Investigation of the Relationship between Electronic Structures and Bioactivities of Polypyridyl Ru (II) Complexes
Z Hou, Y Lu, B Zhang, AFM Motiur Rahman, Y Zhao… - Molecules, 2023 - mdpi.com
Ruthenium (Ru)-based organometallic drugs have gained attention as chemotherapeutic
and bioimaging agents due to their fewer side effects and excellent physical optical …
and bioimaging agents due to their fewer side effects and excellent physical optical …
Ruthenium (II) complexes as mitochondrial inhibitors of topoisomerase induced A549 cell apoptosis
H Tang, X Guo, W Yu, J Gao, X Zhu, Z Huang… - Journal of Inorganic …, 2023 - Elsevier
Two new ruthenium (II) complexes [Ru (dip) 2 (PPβC)] PF 6 (Ru1, dip= 4, 7-diphenyl-1, 10-
phenanthroline, PPβC= N-(1, 10-phenanthrolin-5-yl)-1-phenyl-9H-pyrido [3, 4-b] indole-3 …
phenanthroline, PPβC= N-(1, 10-phenanthrolin-5-yl)-1-phenyl-9H-pyrido [3, 4-b] indole-3 …
Synthesis of N-Alkyl-3-[2-oxoquinolin-1(2H)-yl]propanoic Acid Derivatives and Related Compounds: Cytotoxicity and EGFR Inhibition of Some Propanamide …
SM El Rayes, IAI Ali, W Fathalla, MA Ghanem… - ACS …, 2024 - ACS Publications
A series of 20 new structure-modified quinolin-2-one derivatives were prepared for
biological evaluation. This was successfully achieved based on chemoselective reactions of …
biological evaluation. This was successfully achieved based on chemoselective reactions of …
Synthesis and Characterization of Piano-Stool Ruthenium (II)–Arene Complexes of Isatin Schiff Bases: Cytotoxicity and DNA Intercalation
H Karabıyık, A Karaer Tunçay, S Ilhan, H Atmaca… - ACS …, 2024 - ACS Publications
A series of aryl–isatin Schiff base derivatives (3a–d) and their piano-stool ruthenium
complexes (4a–d) were synthesized and characterized via 1H and 13C NMR and Fourier …
complexes (4a–d) were synthesized and characterized via 1H and 13C NMR and Fourier …
Ruthenium compounds: Are they the next‐era anticancer agents?
SB Kavukcu, CS Özverel, N Kıyak… - Applied …, 2024 - Wiley Online Library
This study focuses on the cytotoxic activity of ruthenium (II) complexes, denoted as Ru1–8,
which exhibit coordination with nitrogen (amine and amide), oxygen, and sulfur donor …
which exhibit coordination with nitrogen (amine and amide), oxygen, and sulfur donor …
Synthesis, spectroscopic characterization, computational and biological evaluation of organometallic Re (I) complexes with 5-(2-butyl-5-chloro-1H-imidazol-4-yl)-1, 3 …
Organometallic rhenium (I) complexes (I-VI) using substituted 5-(2-butyl-5-chloro-1H-
imidazol-4-yl)-1, 3-diaryl-4, 5-dihydro-1H-pyrazole were synthesized and characterized by …
imidazol-4-yl)-1, 3-diaryl-4, 5-dihydro-1H-pyrazole were synthesized and characterized by …
Imidazole/4, 4′-azopyridine bridging binuclear Ru (II) complexes: design, synthesis, bimolecular interactions and cytotoxicity against HeLa cell line
Binuclear Ru (II)-arene complexes [(η6-p cym)(Flq) Ru (μ-im/μ-azpy) Ru (Flq)(η6-p-cym)] Cl
(C1–C8)(cym= cymene; Flq= fluoroquinolones; im= imidazole; azpy= 4, 4′ azo pyridine) …
(C1–C8)(cym= cymene; Flq= fluoroquinolones; im= imidazole; azpy= 4, 4′ azo pyridine) …