Autoantibodies in myositis

NJ McHugh, SL Tansley - Nature Reviews Rheumatology, 2018 - nature.com
The discovery of novel autoantigen systems related to idiopathic inflammatory myopathies
(collectively referred to as myositis) in adults and children has had major implications for the …

Update on outcome assessment in myositis

LG Rider, R Aggarwal, PM Machado… - Nature Reviews …, 2018 - nature.com
The adult and juvenile myositis syndromes, commonly referred to collectively as idiopathic
inflammatory myopathies (IIMs), are systemic autoimmune diseases with the hallmarks of …

Risk factors and disease mechanisms in myositis

FW Miller, JA Lamb, J Schmidt… - Nature Reviews …, 2018 - nature.com
Autoimmune diseases develop as a result of chronic inflammation owing to interactions
between genes and the environment. However, the mechanisms by which autoimmune …

Skeletal muscle provides the immunological micro-milieu for specific plasma cells in anti-synthetase syndrome-associated myositis

C Preuße, B Paesler, C Nelke, D Cengiz… - Acta …, 2022 - Springer
Abstract Anti-synthetase syndrome (ASyS)-associated myositis is a major subgroup of the
idiopathic inflammatory myopathies (IIM) and is characterized by disease chronicity with …

[HTML][HTML] Autoimmune myopathies: updates on evaluation and treatment

ER McGrath, CT Doughty, AA Amato - Neurotherapeutics, 2018 - Elsevier
The major forms of autoimmune myopathies include dermatomyositis (DM), polymyositis
(PM), myositis associated with antisynthetase syndrome (ASS), immune-mediated …

Current perspective on rituximab in rheumatic diseases

T Schioppo, F Ingegnoli - Drug design, development and therapy, 2017 - Taylor & Francis
The steadily increasing knowledge regarding pathogenetic mechanisms in autoimmune
rheumatic diseases has paved the way to different therapeutic approaches. In particular, the …

Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care

C Papadopoulou, C Chew, MGL Wilkinson… - Nature Reviews …, 2023 - nature.com
The childhood-onset or juvenile idiopathic inflammatory myopathies (JIIMs) are a
heterogenous group of rare and serious autoimmune diseases of children and young …

Dermatomyositis and immune-mediated necrotizing myopathies: a window on autoimmunity and cancer

A Aussy, O Boyer, N Cordel - Frontiers in immunology, 2017 - frontiersin.org
Autoimmune myopathies (myositides) are strongly associated with malignancy. The link
between myositis and cancer, originally noticed by Bohan and Peter in their classification in …

Rituximab for refractory rapidly progressive interstitial lung disease related to anti-MDA5 antibody-positive amyopathic dermatomyositis

H So, VTL Wong, VWN Lao, HT Pang, RML Yip - Clinical rheumatology, 2018 - Springer
To report our experience in using rituximab (RTX) for treating refractory rapidly progressive
interstitial lung disease (RP-ILD) complicating anti-melanoma differentiation-associated …

Efficacy and safety of rituximab treatment in patients with idiopathic inflammatory myopathies: A systematic review and meta-analysis

C Zhen, Y Hou, B Zhao, X Ma, T Dai, C Yan - Frontiers in immunology, 2022 - frontiersin.org
Objective Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of
autoimmune diseases with various subtypes, myositis-specific antibodies, and affect multiple …