Cuproptosis was a copper-dependent and unique kind of cell death that was separate from
existing other forms of cell death. The last decade has witnessed a considerable increase in …

Copper is an essential trace element in biological systems, maintaining the activity of
enzymes and the function of transcription factors. However, at high concentrations, copper …

Copper is an essential nutrient whose redox properties make it both beneficial and toxic to
the cell. Recent progress in studying transition metal signalling has forged new links …

Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …

Every cell must satisfy basic requirements for nutrient sensing, utilization and recycling
through macromolecular breakdown to coordinate programmes for growth, repair and stress …

The last 25 years have witnessed tremendous progress in identifying and characterizing
proteins that regulate the uptake, intracellular trafficking and export of copper. Although …

Long known as terminal degradation stations, lysosomes have emerged as sophisticated
signalling centres that govern cell growth, division and differentiation. Lysosomes interface …

Simple Summary Copper is an essential element for human life. However, its redox activity
can be detrimental for the cell that developed highly coordinated pathways to chelate and …

Copper is an essential element in cells; it can act as either a recipient or a donor of
electrons, participating in various reactions. However, an excess of copper ions in cells is …

One of the basic trace elements for the structure and metabolism of human tissue is copper.
However, as a heavy metal, excessive intake or abnormal accumulation of copper in the …