[HTML][HTML] Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame

SJ Borghoff, SS Cohen, X Jiang, IA Lea… - Food and Chemical …, 2023 - Elsevier
Aspartame has been studied extensively and evaluated for its safety in foods and beverages
yet concerns for its potential carcinogenicity have persisted, driven primarily by animal …

The nutraceutical value of carnitine and its use in dietary supplements

A Durazzo, M Lucarini, A Nazhand, SB Souto, AM Silva… - Molecules, 2020 - mdpi.com
Carnitine can be considered a conditionally essential nutrient for its importance in human
physiology. This paper provides an updated picture of the main features of carnitine …

Antioxidant, antiapoptotic, antigenotoxic, and hepatic ameliorative effects of L-carnitine and selenium on cadmium-induced hepatotoxicity and alterations in liver cell …

HSH Abu-El-Zahab, RZ Hamza, MM Montaser… - Ecotoxicology and …, 2019 - Elsevier
L-carnitine (LC) and selenium (Se) have significant protective and antioxidant effects on
several tissues. Cadmium (Cd), widely used in some industries and emitted from fossil fuels …

A mixture of routinely encountered xenobiotics induces both redox adaptations and perturbations in blood and tissues of rats after a long-term low-dose exposure …

P Fountoucidou, AS Veskoukis, E Kerasioti, AO Docea… - Toxicology Letters, 2019 - Elsevier
Exposure of humans to xenobiotic mixtures is a continuous state during their everyday
routine. However, the majority of toxicological studies assess the in vivo effects of individual …

l-Carnitine and vitamin E ameliorate cardiotoxicity induced by tilmicosin in rats

M Aboubakr, F Elsayd, A Soliman, SE Fadl… - … Science and Pollution …, 2020 - Springer
The present study aimed to investigate the possible mitigating effect of l-carnitine (LC)
and/or α-tocopherol (Vit. E) administration against tilmicosin (TIL)-induced cardiotoxicity in …

[HTML][HTML] Syringic acid ameliorates cardiac, hepatic, renal and neuronal damage induced by chronic hyperglycaemia in Wistar rats: a behavioural, biochemical and …

AC Mirza, SS Panchal, AA Allam, SI Othman, M Satia… - Molecules, 2022 - mdpi.com
This study investigated the effects of syringic acid (SA) on renal, cardiac, hepatic, and
neuronal diabetic complications in streptozotocin-induced neonatal (nSTZ) diabetic rats …

Aspartame consumption, mitochondrial disorder-induced impaired ovarian function, and infertility risk

YC Chen, YC Yeh, YF Lin, HK Au, SM Hsia… - International journal of …, 2022 - mdpi.com
Frequent consumption of diet drinks was associated with oocyte dysmorphism, decreased
embryo quality, and an adverse effect on pregnancy rate. We investigated the harmful effects …

Biochemical, histological, and ultrastructural studies of the protective role of vitamin E on cyclophosphamide-induced cardiotoxicity in male rats

AA Attia, JM Sorour, NA Mohamed, TT Mansour… - Biomedicines, 2023 - mdpi.com
Background: Cyclophosphamide (CP)(Cytoxan or Endoxan) is an efficient anti-tumor agent,
widely used for the treatment of various neoplastic diseases. The study aimed to investigate …

[图书][B] Vitagenes in avian biology and poultry health

PF Surai - 2020 - wageningenacademic.com
Commercial poultry production is associated with various types of stress leading to decrease
of productive and reproductive performance and compromised health of growing chickens …

Effect of l-carnitine on cardiotoxicity and apoptosis induced by imatinib through PDGF/PPARγ/MAPK pathways

HH Mansour, AB Ibrahim, MM Omran - Archives of biochemistry and …, 2021 - Elsevier
A tyrosine kinase inhibitor Imatinib (IM) is used in the treatment of different varieties of
cancers. The current study was designed to explore the beneficial role of l-carnitine against …