[HTML][HTML] In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19

H Can, AE Köseoğlu, S Erkunt Alak, M Güvendi… - Scientific reports, 2020 - nature.com
In the genome of SARS-CoV-2, the 5′-terminus encodes a polyprotein, which is further
cleaved into 15 non-structural proteins whereas the 3′ terminus encodes four structural …

[HTML][HTML] Comparative proteomics and secretomics revealed virulence, and coresistance-related factors in non O1/O139 Vibrio cholerae recovered from 16 species of …

X Shan, J Fu, X Li, X Peng, L Chen - Journal of Proteomics, 2022 - Elsevier
Vibrio cholerae can cause pandemic cholera in humans. The bacterium resides in aquatic
environments worldwide. Identification of risk factors of V. cholerae in aquatic products is …

[HTML][HTML] In silico discovery of diagnostic/vaccine candidate antigenic epitopes and a multi-epitope peptide vaccine (NaeVac) design for the brain-eating amoeba …

AE Köseoğlu, F Özgül, EN Işıksal, Y Şeflekçi… - Gene, 2024 - Elsevier
Naegleria fowleri, the brain-eating amoeba, is a free-living amoeboflagellate with three
different life cycles (trophozoite, flagellated, and cyst) that lives in a variety of habitats around …

Design of a multi-epitope vaccine (vme-VAC/MST-1) against cholera and vibriosis based on reverse vaccinology and immunoinformatics approaches

PH Marques, TCV Rodrigues, EH Santos… - Journal of …, 2023 - Taylor & Francis
Vibriosis and cholera are serious diseases distributed worldwide and caused by six marine
bacteria of the Vibrio genus. Thousands of deaths occur each year due to these illnesses …

[HTML][HTML] A Systematic Immuno-Informatic Approach to Design a Multiepitope-Based Vaccine Against Emerging Multiple Drug Resistant Serratia marcescens

MSF Damas, FG Mazur, CCM Freire… - Frontiers in …, 2022 - frontiersin.org
Serratia marcescens is now an important opportunistic pathogen that can cause serious
infections in hospitalized or immunocompromised patients. Here, we used extensive …

A comprehensive examination of ACE2 receptor and prediction of spike glycoprotein and ACE2 interaction based on in silico analysis of ACE2 receptor

E Aktaş, N Özdemir Özgentürk - Journal of Biomolecular Structure …, 2024 - Taylor & Francis
The ACE2 receptor plays a vital role not only in the SARS-CoV-induced epidemic but also in
various other diseases, including cardiovascular diseases and ARDS. While studies have …

Molecular characterization of Anaplasma ovis Msp4 protein in strains isolated from ticks in Turkey: A multi-epitope synthetic vaccine antigen design against …

AE Köseoğlu, H Can, M Güvendi, SE Alak, AD Döşkaya… - Biologicals, 2024 - Elsevier
Tick-borne pathogens increasingly threaten animal and human health as well as cause
great economic loss in the livestock industry. Among these pathogens, Anaplasma ovis …

Bacterial dynamics and network analysis for antigen screening

DLN Rodrigues, JC Ariute, MV Dias… - Reverse …, 2024 - Elsevier
Searching for bacterial-quality antigens must use methodologies that guarantee the
generated products' results and integrity. For this, focusing on vaccinology techniques, it is …

Aggregation prone regions in antibody sequences raised against vibrio cholerae: a bioinformatic approach

Z Akter, A Haque, MS Hossain, F Ahmed… - Current …, 2020 - ingentaconnect.com
Background: Cholera, a diarrheal illness, causes millions of deaths worldwide due to large
outbreaks. The monoclonal antibody used as therapeutic purposes of cholera is prone to be …

[PDF][PDF] Reverse Vaccinology Approach for Vaccine Development Against Streptococcus agalactiae

K Sajjad - 2022 - cust-library.azurewebsites.net
Streptococcus agalactiae is a gram positive bacteria anaerobe, non-spore forming coccus
belongs to streptococcus family (GBS). It is opportunistic and rounded bacteria present in the …