Collective gradient sensing and chemotaxis: modeling and recent developments

BA Camley - Journal of Physics: Condensed Matter, 2018 - iopscience.iop.org
Cells measure a vast variety of signals, from their environment's stiffness to chemical
concentrations and gradients; physical principles strongly limit how accurately they can do …

Clustered cell migration: Modeling the model system of Drosophila border cells

BE Peercy, M Starz-Gaiano - Seminars in cell & developmental biology, 2020 - Elsevier
In diverse developmental contexts, certain cells must migrate to fulfill their roles. Many
questions remain unanswered about the genetic and physical properties that govern cell …

Picking winners in cell-cell collisions: Wetting, speed, and contact

P Zadeh, BA Camley - Physical Review E, 2022 - APS
Groups of eukaryotic cells can coordinate their crawling motion to follow cues more
effectively, stay together, or invade new areas. This collective cell migration depends on cell …

Simple Rho GTPase dynamics generate a complex regulatory landscape associated with cell shape

C Zmurchok, WR Holmes - Biophysical Journal, 2020 - cell.com
Migratory cells exhibit a variety of morphologically distinct responses to their environments
that manifest in their cell shape. Some protrude uniformly to increase substrate contacts …

Differential cell motion: A mathematical model of anterior posterior sorting

J Song, EJ Evans, JC Dallon - Biophysical Journal, 2023 - cell.com
Here, we investigate how a subpopulation of cells can move through an aggregate of cells.
Using a stochastic force-based model of Dictyostelium discoideum when the population is …

Collective gradient sensing with limited positional information

EP Ipiña, BA Camley - Physical Review E, 2022 - APS
Eukaryotic cells sense chemical gradients to decide where and when to move. Clusters of
cells can sense gradients more accurately than individual cells by integrating measurements …

Coalescing clusters unveil regimes of frictional fluid mechanics

H Yue, JC Burton, DM Sussman - Physical Review Research, 2024 - APS
The coalescence of droplets is essential in a host of biological and industrial processes,
where it can be a crucial limiting factor and a convenient tool to probe material properties …

Modeling cell shape diversity arising from complex Rho GTPase dynamics

C Zmurchok, WR Holmes - bioRxiv, 2019 - biorxiv.org
It is well known that cells exhibit a variety of morphologically distinct responses to their
environments that manifest in their cell shape. Some protrude uniformly to increase …