With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …

Most drugs or the natural substances reputed to display some biological activity are
hydrophobic molecules that demonstrate low bioavailability regardless of their mode of …

We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting
of endoplasmic reticulum stress as a potential emerging therapeutic strategy against …

No organism can avoid the process of aging, which is often accompanied by chronic
disease. The process of biological aging is driven by a series of interrelated mechanisms …

It is established that gut microbiota dysbiosis is implicated in arsenic (As)-induced
neurotoxic process, however, the underlying mode of action remains largely unclear. Here …

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a redox-sensitive transcription factor that
binds to the antioxidant response element consensus sequence, decreasing reactive …

Causes of dopaminergic neuronal loss in Parkinson's disease (PD) are subject of
investigation and the common use of models of acute neurodegeneration induced by …

Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive loss of
cognitive functions like thinking, memory, reasoning, behavioral abilities, and social skills …

The growing interest on the therapeutic potential against neurodegeneration of Cannabis
sativa extracts, and of phytocannabinoids in particular, is paralleled by a limited …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is influenced by a variety
of factors, including environmental and genetic factors. The most significant outcome is the …