Background: The risk of upper gastrointestinal (GI) complications associated with the use of
NSAIDs is a serious public health concern. The risk varies between individual NSAIDs; …

Objectives This review attempts to bring together information from a large number of recent
studies on the clinical uses, safety and pharmacological properties of ibuprofen. Ibuprofen is …

Long‐term opioid management for chronic noncancer pain - Noble, M - 2010 | Cochrane
Library Skip to Content Cookies Our site uses cookies to improve your experience. You can …

This widely used text uses a case-based approach to help students master the fundamentals
of drug therapeutics. Students will learn the basics of common diseases and disorders and …

Considerable evidence gained over the past decade has supported the conclusion that
neuroinflammation is associated with Alzheimer's disease (AD) pathology. Inflammatory …

BACKGROUND: Osteoarthritis (OA) is the most common cause of disability in older adults,
and although analgesic use can be helpful, it can also result in adverse drug events …

Background: The risks and benefits of coxibs, non-steroidal anti-inflammatory drugs
(NSAIDs), and aspirin treatment are under intense debate. Objective: To determine the risk …

Iron deficiency anemia (IDA) is associated with a number of pathological gastrointestinal
conditions other than inflammatory bowel disease, and also with liver disorders. Different …

Osteoarthritis (OA) is currently defined by the American College of Rheumatology as a
“heterogeneous group of conditions that leads to joint symptoms and signs which are …

Aim: The relative gastrointestinal toxicity of NSAIDs in normal clinical practice is unknown.
The aim of this study was to estimate the risk of upper gastrointestinal bleeding associated …