Tuberculosis (TB) is a contagious and airborne infectious disease caused by the pathogen
Mycobacterium tuberculosis (Mtb). In spite of substantial research efforts, continuous …

Vaccines are a very important tool in the effort to reduce the global burden of infectious
diseases. Modern vaccines can be formulated in several ways to induce specific immunity …

Systemic administration of antifungal agents for the treatment of pulmonary aspergillosis is
limited by the poor lung deposition and severe adverse effects. In contrast, pulmonary …

Tuberculosis (TB) is a major global health burden. The emergence of the human
immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB …

Dry powder inhalers (DPI) are widely used systems for pulmonary delivery of therapeutics.
The inhalation performance of DPIs is influenced by formulation features, inhaler device and …

Microparticulate formulations of intranasal drug administration, ie nasal powder, have
aroused widespread interest in academia and industry. However, low drug bioavailability …

Incorporating anthocyanins, valuable natural pigments, into a powder can improve their
stability, but exposure to high temperatures during processing can cause them to degrade …

Drug-resistant tuberculosis (DR-TB) is an emerging health problem, challenging the
effective control of global TB. Current treatment of DR-TB includes administration of multiple …

Pulmonary delivery of small interfering RNAs (siRNAs) has shown promising results for the
treatment of lung diseases with gene disorders. The aim of this work was to evaluate the …

Inhaled drug delivery is a promising approach to achieving high lung drug concentrations to
facilitate efficient treatment of tuberculosis (TB) and to reduce the overall duration of …