Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

DA Wink, JB Mitchell - Free Radical Biology and Medicine, 1998 - Elsevier
There has been confusion as to what role (s) nitric oxide (NO) has in different physiological
and pathophysiological mechanisms. Some studies imply that NO has cytotoxic properties …

[图书][B] Oxidation and antioxidants in organic chemistry and biology

ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

The role of nitric oxide in cardiovascular diseases

KM Naseem - Molecular aspects of medicine, 2005 - Elsevier
Nitric oxide (NO) is a gaseous lipophilic free radical cellular messenger generated by three
distinct isoforms of nitric oxide synthases (NOS), neuronal (nNOS), inducible (iNOS) and …

A study of the mechanisms underlying the anti-inflammatory effect of ellagic acid in carrageenan-induced paw edema in rats

MT Mansouri, AA Hemmati, B Naghizadeh… - Indian journal of …, 2015 - journals.lww.com
Objectives: Ellagic acid (EA) has shown antinociceptive and anti-inflammatory effects.
Inducible nitric oxide synthase (iNOS), cyclooxygenase 2 (COX-2) enzymes and also …

Nitric oxide: a key mediator in the early and late phase of carrageenan‐induced rat paw inflammation

D Salvemini, ZQ Wang, PS Wyatt… - British journal of …, 1996 - Wiley Online Library
1 The role of nitric oxide (NO) derived from constitutive and inducible nitric oxide synthase
(cNOS and iNOS) and its relationship to oxygen‐derived free radicals and prostaglandins …

Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin

T Murohara, JR Horowitz, M Silver, Y Tsurumi, D Chen… - Circulation, 1998 - Am Heart Assoc
Background—Vascular endothelial growth factor (VEGF), an endothelial cell mitogen that
promotes angiogenesis, was initially identified as a vascular permeability factor (VPF) …

Quercetin attenuates atherosclerotic inflammation and adhesion molecule expression by modulating TLR-NF-κB signaling pathway

S Bhaskar, PR Sudhakaran, A Helen - Cellular immunology, 2016 - Elsevier
Adhesion molecules expressed by activated endothelial cells play key role in regulating
leukocyte trafficking to sites of inflammation. The present study attempted to explore whether …

Neurovascular dysfunction in glaucoma

L Alarcon-Martinez, Y Shiga… - Progress in Retinal and …, 2023 - Elsevier
Retinal ganglion cells, the neurons that die in glaucoma, are endowed with a high
metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The …

Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors

V Mollace, C Muscoli, E Masini, S Cuzzocrea… - Pharmacological …, 2005 - ASPET
The biosynthesis and release of nitric oxide (NO) and prostaglandins (PGs) share a number
of similarities. Two major forms of nitric-oxide synthase (NOS) and cyclooxygenase (COX) …

[HTML][HTML] Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src

H He, VJ Venema, X Gu, RC Venema… - Journal of Biological …, 1999 - ASBMB
Vascular endothelial growth factor (VEGF) is a potent endothelial cell-specific mitogen that
promotes angiogenesis, vascular hyperpermeability, and vasodilation by autocrine …