Long-lived states of methylene protons in achiral molecules

A Sonnefeld, A Razanahoera, P Pelupessy… - Science …, 2022 - science.org
In nuclear magnetic resonance (NMR), the lifetimes of long-lived states (LLSs) are
exquisitely sensitive to their environment. However, the number of molecules where such …

Singlet-filtered NMR spectroscopy

S Mamone, N Rezaei-Ghaleh, F Opazo… - Science …, 2020 - science.org
Selectively studying parts of proteins and metabolites in tissue with nuclear magnetic
resonance promises new insights into molecular structures or diagnostic approaches …

Polychromatic excitation of delocalized long-lived proton spin states in aliphatic chains

A Sonnefeld, G Bodenhausen, K Sheberstov - Physical Review Letters, 2022 - APS
Long-lived states (LLS) involving pairs of magnetically inequivalent but chemically
equivalent proton spins in aliphatic (CH 2) n chains can be excited by simultaneous …

Constant-adiabaticity radiofrequency pulses for generating long-lived singlet spin states in NMR

BA Rodin, KF Sheberstov, AS Kiryutin… - The Journal of …, 2019 - pubs.aip.org
A method is implemented to perform “fast” adiabatic variation of the spin Hamiltonian by
imposing the constant adiabaticity condition. The method is applied to improve the …

Selective filtration of NMR signals arising from weakly-and strongly-coupled spin systems

J Lu, A Jerschow, DE Korenchan - Journal of Magnetic Resonance, 2023 - Elsevier
Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique for analyzing
chemical and biological systems. However, in complex solutions with similar molecular …

In vivo singlet state filtered nuclear magnetic resonance: towards monitoring toxic responses inside living organisms

DH Lysak, FVC Kock, S Mamone, R Soong… - Chemical …, 2023 - pubs.rsc.org
In line with recent paradigm shifts in toxicity testing, in vivo nuclear magnetic resonance
(NMR) is a powerful tool for studying the biological impacts and perturbations caused by …

31 P nuclear spin singlet lifetimes in a system with switchable magnetic inequivalence: experiment and simulation

DE Korenchan, J Lu, MH Levitt… - Physical Chemistry …, 2021 - pubs.rsc.org
31P NMR spectroscopy and the study of nuclear spin singlet relaxation phenomena are of
interest in particular due to the importance of phosphorus-containing compounds in …

Ultrafast Single‐Scan 2D NMR Spectroscopic Detection of a PHIP‐Hyperpolarized Protease Inhibitor

AS Kiryutin, G Sauer, D Tietze… - … A European Journal, 2019 - Wiley Online Library
Two‐dimensional NMR spectroscopy is one of the most important spectroscopic tools for the
investigation of biological macromolecules. However, due to the low sensitivity of NMR …

Adaptable singlet-filtered nuclear magnetic resonance spectroscopy for chemical and biological applications

C Huang, Y Peng, E Lin, Z Ni, X Lin, H Zhan… - Analytical …, 2022 - ACS Publications
Proton nuclear magnetic resonance (1H NMR) spectroscopy presents a powerful detection
tool for studying chemical compositions and molecular structures. In practical chemical and …

Using optimal control methods with constraints to generate singlet states in NMR

BA Rodin, AS Kiryutin, AV Yurkovskaya… - Journal of Magnetic …, 2018 - Elsevier
A method is proposed for optimizing the performance of the APSOC (Adiabatic-Passage
Spin Order Conversion) technique, which can be exploited in NMR experiments with singlet …