Clinical management of metastatic colorectal cancer in the era of precision medicine

F Ciardiello, D Ciardiello, G Martini… - CA: a cancer journal …, 2022 - Wiley Online Library
Colorectal cancer (CRC) represents approximately 10% of all cancers and is the second
most common cause of cancer deaths. Initial clinical presentation as metastatic CRC …

[HTML][HTML] Comprehensive review of targeted therapy for colorectal cancer

YH Xie, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …

Colon cancer, version 2.2021, NCCN clinical practice guidelines in oncology

AB Benson, AP Venook, MM Al-Hawary… - Journal of the National …, 2021 - jnccn.org
This selection from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines)
for Colon Cancer focuses on systemic therapy options for the treatment of metastatic …

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

A Cervantes, R Adam, S Roselló, D Arnold… - Annals of …, 2023 - annalsofoncology.org
Colorectal cancer (CRC) is the third most common cancer worldwide, with 1.1 million new
cases per year and is the second leading cause of cancer death. 1 CRC occurs more …

[HTML][HTML] Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer

Y Hashiguchi, K Muro, Y Saito, Y Ito, Y Ajioka… - International journal of …, 2020 - Springer
The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

Biomarker-guided therapy for colorectal cancer: strength in complexity

A Sveen, S Kopetz, RA Lothe - Nature Reviews Clinical Oncology, 2020 - nature.com
The number of molecularly stratified treatment options available to patients with colorectal
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …

Modern therapeutic approaches for the treatment of malignant liver tumours

H Petrowsky, R Fritsch, M Guckenberger… - Nature reviews …, 2020 - nature.com
Malignant liver tumours include a wide range of primary and secondary tumours. Although
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …

[HTML][HTML] Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by …

T Yoshino, D Arnold, H Taniguchi, G Pentheroudakis… - Annals of …, 2018 - Elsevier
The most recent version of the European Society for Medical Oncology (ESMO) consensus
guidelines for the treatment of patients with metastatic colorectal cancer (mCRC) was …

[HTML][HTML] Mutational analysis of patients with colorectal cancer in CALGB/SWOG 80405 identifies new roles of microsatellite instability and tumor mutational burden for …

F Innocenti, FS Ou, X Qu, TJ Zemla… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
PURPOSE CALGB/SWOG 80405 was a randomized phase III trial that found no statistically
significant difference in overall survival (OS) in patients with first-line metastatic colorectal …

[HTML][HTML] Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre …

JA Bridgewater, SA Pugh, T Maishman… - The lancet …, 2020 - thelancet.com
Background The interim analysis of the multicentre New EPOC trial in patients with
resectable colorectal liver metastasis showed a significant reduction in progression-free …