[HTML][HTML] Progress on denosumab use in giant cell tumor of bone: dose and duration of therapy

F Xiang, H Liu, J Deng, W Ma, Y Chen - Cancers, 2022 - mdpi.com
Simple Summary Giant cell tumor of bone (GCTB) is an aggressive non-cancerous bone
tumor. Surgery remains the main treatment for GCTB. Denosumab has been approved for …

[HTML][HTML] Integrating coaxial electrospinning and 3D printing technologies for the development of biphasic porous scaffolds enabling spatiotemporal control in tumor …

W He, C Li, S Zhao, Z Li, J Wu, J Li, H Zhou, Y Yang… - Bioactive Materials, 2024 - Elsevier
The osteochondral defects (OCDs) resulting from the treatment of giant cell tumors of bone
(GCTB) often present two challenges for clinicians: tumor residue leading to local recurrence …

The dual role of MiR-210 in the aetiology of cancer: A focus on hypoxia-inducible factor signalling

S Afsar, RU Syed, MKB Break, RH Alsukaybi… - … -Research and Practice, 2023 - Elsevier
Tumorigenesis exemplifies the complex process of neoplasm origination, which is
characterised by somatic genetic alterations and abnormal cellular growth. This …

[HTML][HTML] Giant cell tumor (osteoclastoma)

S Hosseinzadeh, V Tiwari, O De Jesus - 2024 - europepmc.org
Giant Cell Tumor (Osteoclastoma) Shayan Hosseinzadeh; Vivek Tiwari; Orlando De Jesus.
Author Information Last Update: January 31, 2024. Continuing Education Activity Giant cell …

[HTML][HTML] Management of a rare mandibular giant cell tumor of bone by neoadjuvant denosumab therapy and surgery: a 4-year follow-up case report

P Klienkoff, N Weingertner, L Geyer, CI Gros… - International Journal of …, 2023 - Elsevier
Introduction Giant cell tumor of bone (GCTB) is a very rare tumor encountered in the jaws
and its histology is quite similar to the more common giant cell granuloma of the jaws …

[HTML][HTML] Emerging trends and focus of giant cell tumor of bone research from 2001–2021: A visualization research

YS Han, YF Yang, G Chen, HL Yu, ZG Zhang… - Frontiers in …, 2022 - frontiersin.org
Giant cell tumor of bone is a highly invasive benign tumor with a high postoperative
recurrence rate. Objective: This study aims to analyze the research hotspots and trends of …

The effect of preoperative embolization on giant cell tumors of the bone localized in the iliosacral region of the pelvis

F Scheurer, D Kaiser, A Kobe, M Smolle, D Suter… - Surgical Oncology, 2024 - Elsevier
Introduction Giant cell tumors of the bone (GCTB) are aggressive neoplasms, with rare
occurrences in the posterior pelvis and sacral area. Surgical challenges in this region …

[HTML][HTML] Characterization of denosumab treatment response in giant cell tumors of bone with dynamic contrast-enhanced MRI

GM Kalisvaart, L van der Heijden, AN Cañete… - European Journal of …, 2023 - Elsevier
Rationale and objectives Denosumab is a monoclonal antibody used neo-adjuvantly in
giant cell tumor of bone (GCTB) to facilitate surgery, or long term for axial tumors where …

[HTML][HTML] A technical note on autologous iliac crest bone grafting for restoration of the distal tibial articular surface

BZ Hasan, MK Mesregah - Journal of Experimental Orthopaedics, 2023 - Springer
Purpose This technical note describes a reconstructive technique of the distal tibial articular
surface using autologous iliac crest bone graft. Methods Following curettage and high …

Surgical Strategy for Recurrent Giant Cell Tumor in the Thoracolumbar Spine

A Leng, M Yang, H Sun, Z Dai, Z Zhu… - Orthopaedic …, 2024 - Wiley Online Library
Objective Recurrent giant cell tumor (RGCT) of the spine represents a clinical challenge for
surgeons, and the treatment strategy remains controversial. This study aims to describe the …