Potential impact of the multi-target drug approach in the treatment of some complex diseases
It is essential to acknowledge the efforts made thus far to manage or eliminate various
disease burden faced by humankind. However, the rising global trends of the so-called …
disease burden faced by humankind. However, the rising global trends of the so-called …
The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus
SS Mkhize, MB Cedric Simelane… - Biochemistry …, 2022 - Wiley Online Library
Pleurotus ostreatus mushroom contains important bioactive compounds and has several
biological activities; however, mushroom growing substrates have major influence on …
biological activities; however, mushroom growing substrates have major influence on …
[HTML][HTML] Toxicity and phytochemical properties of southern African medicinal plants used traditionally to treat pain and inflammatory ailments
GP Khumalo, BE Van Wyk, Y Feng, IE Cock - South African Journal of …, 2023 - Elsevier
The harmful side effects associated with conventional anti-inflammatory pharmaceuticals
has focussed attention on medicinal plants as alternative therapeutics. However, the use of …
has focussed attention on medicinal plants as alternative therapeutics. However, the use of …
[HTML][HTML] Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1
Plasmodium falciparum is the most lethal malaria parasite. The present study investigates
the interaction capabilities of select plant derivatives, iso-mukaadial acetate (IMA) and …
the interaction capabilities of select plant derivatives, iso-mukaadial acetate (IMA) and …
Bioprospecting the Biological Effects of Cultivating Pleurotus ostreatus Mushrooms from Selected Agro‐Wastes and Maize Flour Supplements
SS Mkhize, MBC Simelane… - Journal of Food …, 2023 - Wiley Online Library
Pleurotus mushrooms are valuable food supplements with health and environmental
restorative potential. In this paper, we sought to evaluate the biological activities and profile …
restorative potential. In this paper, we sought to evaluate the biological activities and profile …
[HTML][HTML] Bioprospecting the liver protective activity of betulinic acid isolated from the stem bark of Ziziphus mucronata Willd. subsp. mucronata
Abstract In traditional African medicine, Ziziphus mucronata Willd. subsp. mucronata is used
in the treatment of chronic cough, boils, toothache, rheumatism, diabetes, hypertension …
in the treatment of chronic cough, boils, toothache, rheumatism, diabetes, hypertension …
Evaluation of 100 most cited research articles on African medicinal plants
K Okaiyeto, OO Oguntibeju - Plant Science Today, 2021 - horizonepublishing.com
The mission for drug discovery and progress has prompt researchers to scientifically
validate the therapeutic uses of medicinal plants available worldwide, of which, African …
validate the therapeutic uses of medicinal plants available worldwide, of which, African …
Mushroom‐derived products as an alternative antimalarial therapeutics: A Review
SS Mkhize, KE Machaba… - Drug Development for …, 2022 - Wiley Online Library
Edible and medicinal mushrooms have been highlighted to contain potent antiparasitic
activity, due to their vast phytochemical content. Mushroom can be defined as a macro …
activity, due to their vast phytochemical content. Mushroom can be defined as a macro …
Evaluating the antioxidant and heavy metal content of Pleurotus ostreatus mushrooms cultivated using sugar cane agro-waste
SS Mkhize, MBC Simelane, NL Gasa… - Pharmacognosy …, 2021 - phcogj.com
Background: Pleurotus ostreatus, is one of the most cultivated mushrooms with great
economic and medicinal value that can be easily grown on various bio-waste substrates …
economic and medicinal value that can be easily grown on various bio-waste substrates …
[PDF][PDF] Chemical Elucidation, Microbial Growth and Free Radical Inhibitory Effects of Dennettia tripetala Fruit: In vitro and In vivo Model Experiments.
Natural products are being exploited in the treatment of diverse ailments stemming from
microbial and free radical incursion in the African native societies. The current study was …
microbial and free radical incursion in the African native societies. The current study was …