The role of cyclodextrins in COVID-19 therapy—a literature review

B Almeida, C Domingues, F Mascarenhas-Melo… - International Journal of …, 2023 - mdpi.com
Coronavirus disease-19 (COVID-19) emerged in December 2019 and quickly spread, giving
rise to a pandemic crisis. Therefore, it triggered tireless efforts to identify the mechanisms of …

[HTML][HTML] The bidirectional interaction of COVID-19 infections and lipoproteins

KR Feingold - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
COVID-19 infections decrease total cholesterol, LDL-C, HDL-C, and apolipoprotein AI, A-II,
and B levels while triglyceride levels may be increased or inappropriately normal for the …

[HTML][HTML] A reliable stochastic computational procedure to solve the mathematical robotic model

Z Sabir, SB Said, Q Al-Mdallal, SA Bhat - Expert Systems with Applications, 2024 - Elsevier
The current work presents the numerical solutions of the robotic system in the process of
coronavirus. The stochastic performances using the modeling of Gudermannian neural …

A neural network computational structure for the fractional order breast cancer model

Z Huang, Q Haider, Z Sabir, M Arshad, BK Siddiqui… - Scientific Reports, 2023 - nature.com
The current study provides the numerical performances of the fractional kind of breast
cancer (FKBC) model, which are based on five different classes including cancer stem cells …

Gut-liver axis calibrates intestinal stem cell fitness

G Kim, Z Chen, J Li, J Luo, F Castro-Martinez… - Cell, 2024 - cell.com
The gut and liver are recognized to mutually communicate through the biliary tract, portal
vein, and systemic circulation. However, it remains unclear how this gut-liver axis regulates …

Mapping the Lipid Signatures in COVID-19 Infection: Diagnostic and Therapeutic Solutions

A Dasgupta, S Gangai, R Narayan… - Journal of Medicinal …, 2023 - ACS Publications
The COVID-19 pandemic ignited research centered around the identification of robust
biomarkers and therapeutic targets. SARS-CoV-2, the virus responsible, hijacks the …

Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections

SJ Hurwitz, R De, JC LeCher, JA Downs-Bowen… - Viruses, 2024 - mdpi.com
Most repurposed drugs have proved ineffective for treating COVID-19. We evaluated median
effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical …

Familial hypercholesterolemia: the nexus of endothelial dysfunction and lipoprotein metabolism in COVID-19

A Vuorio, F Raal, PT Kovanen - Current Opinion in Lipidology, 2023 - journals.lww.com
Epidemiologic registry data show that the incidence of myocardial infarction is increased in
SARS-CoV-2-infected HeFH patients. There is a need to study whether the risk for acute …

[HTML][HTML] Nanotechnology in inflammation: cutting-edge advances in diagnostics, therapeutics and theranostics

Y Liu, Z Lin, Y Wang, L Chen, Y Wang, C Luo - Theranostics, 2024 - ncbi.nlm.nih.gov
Inflammatory dysregulation is intimately associated with the occurrence and progression of
many life-threatening diseases. Accurate detection and timely therapeutic intervention on …

Treating COVID-19: targeting the host response, not the virus

DS Fedson - Life, 2023 - mdpi.com
In low-and middle-income countries (LMICs), inexpensive generic drugs like statins, ACE
inhibitors, and ARBs, especially if used in combination, might be the only practical way to …