Antimicrobial photodynamic therapy to control clinically relevant biofilm infections

X Hu, YY Huang, Y Wang, X Wang… - Frontiers in …, 2018 - frontiersin.org
Biofilm describes a microbially-derived sessile community in which microbial cells are firmly
attached to the substratum and embedded in extracellular polymeric matrix. Microbial …

Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options

JCO Sardi, L Scorzoni, T Bernardi… - Journal of medical …, 2013 - microbiologyresearch.org
The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

JM Dąbrowski, B Pucelik, A Regiel-Futyra… - Coordination Chemistry …, 2016 - Elsevier
Applications of metalloporphyrins and related molecules have been extensively pursued in
the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This …

Antimicrobial photodynamic therapy for inactivation of biofilms formed by oral key pathogens

F Cieplik, L Tabenski, W Buchalla… - Frontiers in microbiology, 2014 - frontiersin.org
With increasing numbers of antibiotic-resistant pathogens all over the world there is a
pressing need for strategies that are capable of inactivating biofilm-state pathogens with less …

Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond

R Yin, T Dai, P Avci, AES Jorge, WCMA De Melo… - Current opinion in …, 2013 - Elsevier
Highlights•Light-based anti-infectives work against biofilms and localized
infections.•Ultraviolet C light will kill all pathogens without killing host mammalian …

Photoactive antimicrobial nanomaterials

Y Feng, L Liu, J Zhang, H Aslan, M Dong - Journal of Materials …, 2017 - pubs.rsc.org
Pathogenic microbes cause infections and are excellent at adapting to the disinfection
strategies that address their biochemistry. The growth in number of drug resistant superbugs …

Porphyrin nanoemulsion for antimicrobial photodynamic therapy: effective delivery to inactivate biofilm-related infections

HH Buzzá, F Alves, AJB Tomé, J Chen… - Proceedings of the …, 2022 - National Acad Sciences
The management of biofilm-related infections is a challenge in healthcare, and antimicrobial
photodynamic therapy (aPDT) is a powerful tool that has demonstrated a broad-spectrum …

Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection

WCMA De Melo, P Avci, MN De Oliveira… - Expert review of anti …, 2013 - Taylor & Francis
Microbial biofilms are responsible for a variety of microbial infections in different parts of the
body, such as urinary tract infections, catheter infections, middle-ear infections, gingivitis …

Antimicrobial photosensitizers: drug discovery under the spotlight

R Yin, M R. Hamblin - Current medicinal chemistry, 2015 - benthamdirect.com
Although photodynamic therapy (PDT) was discovered over a hundred years ago by its
ability to destroy microorganisms, it has been developed mainly as a cancer therapy. In …

Photosensitizers mediated photodynamic inactivation against fungi

D Ziental, DT Mlynarczyk, B Czarczynska-Goslinska… - Nanomaterials, 2021 - mdpi.com
Superficial and systemic fungal infections are essential problems for the modern health care
system. One of the challenges is the growing resistance of fungi to classic antifungals and …