Ischaemic stroke
Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …
Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data
BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …
Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke
H Ma, BCV Campbell, MW Parsons… - … England Journal of …, 2019 - Mass Medical Soc
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …
[HTML][HTML] Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis
JM Wardlaw, V Murray, E Berge, G Del Zoppo… - The Lancet, 2012 - thelancet.com
Background Recombinant tissue plasminogen activator (rt-PA, alteplase) improved
functional outcome in patients treated soon after acute ischaemic stroke in randomised trials …
functional outcome in patients treated soon after acute ischaemic stroke in randomised trials …
Thrombolysis for acute ischaemic stroke
JM Wardlaw, V Murray, E Berge… - Cochrane database of …, 2014 - cochranelibrary.com
Background Most strokes are due to blockage of an artery in the brain by a blood clot.
Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage …
Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage …
Comparison of computed tomography perfusion and magnetic resonance imaging perfusion-diffusion mismatch in ischemic stroke
BCV Campbell, S Christensen, CR Levi, PM Desmond… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Perfusion imaging has the potential to select patients most likely
to respond to thrombolysis. We tested the correspondence of computed tomography …
to respond to thrombolysis. We tested the correspondence of computed tomography …
Whole-brain CT perfusion to quantify acute ischemic penumbra and core
Purpose To validate the use of perfusion computed tomography (CT) with whole-brain
coverage to measure the ischemic penumbra and core and to compare its performance to …
coverage to measure the ischemic penumbra and core and to compare its performance to …
Role of imaging in current acute ischemic stroke workflow for endovascular therapy
Ischemic stroke is caused by a thrombus that blocks an intracranial artery. Brain tissue
beyond the blocked artery survives for a variable period of time because of blood and …
beyond the blocked artery survives for a variable period of time because of blood and …
Intravenous thrombolysis for acute ischemic stroke within 3 hours versus between 3 and 4.5 hours of symptom onset
NT Cheng, AS Kim - The Neurohospitalist, 2015 - journals.sagepub.com
Data from randomized clinical trials have supported the safety and efficacy of intravenous
tissue-type plasminogen activator (IV tPA) for acute ischemic stroke when administered …
tissue-type plasminogen activator (IV tPA) for acute ischemic stroke when administered …
Machine learning–enabled automated determination of acute ischemic core from computed tomography angiography
Background and Purpose—The availability of and expertise to interpret advanced
neuroimaging recommended in the guideline-based endovascular stroke therapy (EST) …
neuroimaging recommended in the guideline-based endovascular stroke therapy (EST) …