Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Cyclodextrins are able to act as host molecules in supramolecular chemistry with
applications ranging from pharmaceutics to detergency. Among guest molecules surfactants …

Introduction Most new drug candidates under development are poorly water-soluble, which
are related to multiple pharmaceutical issues, increasing the bioavailability of these drugs by …

Cyclodextrins (CDs) play an important role in self-assembly systems of amphiphiles. The
structure of CDs provides distinguished physicochemical properties, including the ability to …

Migraine is a widespread neurological disease with negative effects on quality of life and
productivity. Moderate to severe acute migraine attacks can be treated with …

Purpose The aim of this study was to formulate a hydrogel loaded with polymeric
nanoparticles (PoNPs) of simvastatin (SIM) for topical wound healing application. Materials …

Electrospun multilayer nanofibers guided bone regeneration (GBR) with a new design were
developed in this study. The synthesized multilayer GBR was composed of two distinct …

The study was designed to investigate the feasibility of supercritical carbon dioxide (scCO2)
processing for the preparation of simvastatin (SIM) solid dispersions (SDs) in …

Novel water-soluble inclusion complexes for fisetin (FIT) were developed by introducing β-
cyclodextrin (β-CD) and γ-CD. Properties of the obtained complexes, as well as the …

An increasing number of studies published so far have evidenced the benefits of Simvastatin
(SIM) and Doxorubicin (DOX) co-treatment in colorectal cancer. In view of this, the current …