Current studies on molecular mechanisms of insulin resistance
J Pei, B Wang, D Wang - Journal of Diabetes Research, 2022 - Wiley Online Library
Diabetes is a metabolic disease that raises the risk of microvascular and neurological
disorders. Insensitivity to insulin is a characteristic of type II diabetes, which accounts for 85 …
disorders. Insensitivity to insulin is a characteristic of type II diabetes, which accounts for 85 …
Association between genetic variants and diabetes mellitus in Iranian populations: a systematic review of observational studies
M Khodaeian, S Enayati… - Journal of diabetes …, 2015 - Wiley Online Library
Introduction. Diabetes mellitus as the most prevalent metabolic disease is a multifactorial
disease which is influenced by environmental and genetic factors. In this systematic review …
disease which is influenced by environmental and genetic factors. In this systematic review …
Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population
I Akhlaghipour, AR Bina, MR Mogharrabi, A Fanoodi… - Human Genomics, 2022 - Springer
Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …
[PDF][PDF] Association of rs7903146, rs12255372, and rs290487 polymorphisms in TCF7L2 gene with type 2 diabetes in an Iranian Kurdish ethnic group
S Shokouhi, A Delpisheh, K Haghani, M Mahdizadeh… - Clin Lab, 2014 - core.ac.uk
SUMMARY Background: Single nucleotide polymorphisms (SNPs) within the transcription
factor 7-like 2 (TCF7L2) gene are well known risk variants for type 2 diabetes mellitus …
factor 7-like 2 (TCF7L2) gene are well known risk variants for type 2 diabetes mellitus …
[HTML][HTML] Association of TNF-α 308 G/A polymorphism with type 2 diabetes: a case–control study in the iranian kurdish ethnic group
H Golshani, K Haghani, M Dousti… - Osong public health and …, 2015 - Elsevier
Objectives Tumor necrosis factor-α (TNF-α) plays roles in the development of obesity, insulin
resistance, and possibility of Type 2 diabetes mellitus (T2DM). The objective of the current …
resistance, and possibility of Type 2 diabetes mellitus (T2DM). The objective of the current …
Work-family conflict and sleep disturbance: the Malaysian working women study
S Aazami, M Mozafari, K Shamsuddin, S Akmal - Industrial health, 2016 - jstage.jst.go.jp
This study aimed at assessing effect of the four dimensions of work-family conflicts (strain
and time-based work interference into family and family interference into work) on sleep …
and time-based work interference into family and family interference into work) on sleep …
The combined role of allelic variants of IRS-1 and IRS-2 genes in susceptibility to type2 diabetes in the Punjabi Pakistani subjects
A Ijaz, S Babar, S Sarwar, SU Shahid… - Diabetology & metabolic …, 2019 - Springer
Background Diabetes mellitus is a multifactorial disorder characterized by a high level of
glucose in the blood. Both genetic and environmental factors interact to cause diabetes …
glucose in the blood. Both genetic and environmental factors interact to cause diabetes …
Association between PGC-1alpha gene polymorphisms and type 2 diabetes risk: a case-control study of an Iranian population
S Shokouhi, K Haghani, P Borji, S Bakhtiyari - Canadian journal of diabetes, 2015 - Elsevier
Objective The peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-
1alpha) gene could play a role in the onset of type 2 diabetes mellitus. The aim of this study …
1alpha) gene could play a role in the onset of type 2 diabetes mellitus. The aim of this study …
Association of IRS-1 and IRS-2 polymorphisms with predisposition to type-2 diabetes (T2D): a meta-analysis and trial sequential analysis
Q Luo, Z Ling, X Huang, Y Zuo - Nucleosides, Nucleotides & …, 2023 - Taylor & Francis
Abstract Background: Insulin Receptor Substrate (IRS) molecules play a major role in insulin
signalling, and single nucleotide polymorphisms in the IRS-1 (rs1801278) and IRS-2 …
signalling, and single nucleotide polymorphisms in the IRS-1 (rs1801278) and IRS-2 …
Associations between two single-nucleotide polymorphisms (rs1801278 and rs2943641) of insulin receptor substrate 1 gene and type 2 diabetes susceptibility: a meta …
Q Li, Y Qiao, C Wang, G Zhang, X Zhang, L Xu - Endocrine, 2016 - Springer
The objective of the study is to assess the association between rs1801278 and rs2943641 of
insulin receptor substrate 1 gene (IRS1) and the susceptibility to type 2 diabetes. A literature …
insulin receptor substrate 1 gene (IRS1) and the susceptibility to type 2 diabetes. A literature …