The adipose tissue as an endocrine organ

M Adamczak, A Wiecek - Seminars in nephrology, 2013 - Elsevier
During the past 2 decades, results of both basic science and clinical studies have changed
the physicians' views about adipocyte pathophysiology. Since leptin was discovered in …

[HTML][HTML] Pathophysiology of non alcoholic fatty liver disease

S Petta, A Gastaldelli, E Rebelos, E Bugianesi… - International journal of …, 2016 - mdpi.com
The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style
and inflammation, which have a major impact on the severity of the clinicopathologic …

Adiponectin in inflammatory and immune-mediated diseases

G Fantuzzi - Cytokine, 2013 - Elsevier
Circulating levels of adiponectin (APN) are reduced in obesity and associated comorbidities,
with inflammation playing an important role in downregulating APN production. In contrast to …

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

S Shetty, CM Kusminski, PE Scherer - Trends in pharmacological sciences, 2009 - cell.com
Adiponectin is a secretory protein predominantly expressed by adipocytes and released at a
high rate into circulation. The ease with which the levels of adiponectin can be measured …

Prognostic value of adiponectin for cardiovascular disease and mortality

JM Dekker, T Funahashi, G Nijpels… - The Journal of …, 2008 - academic.oup.com
Context: Low adiponectin concentrations are associated with the presence of an adverse
cardiovascular disease (CVD) risk profile. Objective: We studied the predictive value of …

[HTML][HTML] Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus

BH Rovin, H Song, LA Hebert, T Nadasdy… - Kidney international, 2005 - Elsevier
Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus.
Background Adiponectin is an adipocyte-derived cytokine that has anti-inflammatory …

Serum visfatin concentration and endothelial dysfunction in chronic kidney disease

MI Yilmaz, M Saglam, JJ Carrero… - Nephrology dialysis …, 2008 - academic.oup.com
Background. Endothelial dysfunction (ED) is common in patients with moderate to advanced
chronic kidney disease (CKD). Recently, visfatin, a protein with insulin-mimetic properties …

Serum concentrations of leptin, adiponectin and resistin, and their relationship with cardiovascular disease in patients with end‐stage renal disease

JJ Díez, P Iglesias, MJ Fernández‐Reyes… - Clinical …, 2005 - Wiley Online Library
Summary Background and Objective High levels of some adipocytokines have been
reported in patients with chronic renal failure, but little information is available on …

Adiponectin and mortality in patients undergoing coronary angiography

S Pilz, H Mangge, B Wellnitz, U Seelhorst… - The Journal of …, 2006 - academic.oup.com
Context: The adipokine adiponectin has been suggested to protect against coronary artery
disease (CAD). However, studies addressing the association between adiponectin and …

The role of the adipocyte hormone adiponectin in cardiovascular disease

C Hug, HF Lodish - Current opinion in pharmacology, 2005 - Elsevier
Adiponectin, a novel hormone made by fat tissue, regulates energy metabolism and
endothelial activation. Serum levels of adiponectin are reduced in conditions that are …