[HTML][HTML] Host-directed therapies for bacterial and viral infections
SHE Kaufmann, A Dorhoi, RS Hotchkiss… - Nature reviews Drug …, 2018 - nature.com
Despite the recent increase in the development of antivirals and antibiotics, antimicrobial
resistance and the lack of broad-spectrum virus-targeting drugs are still important issues and …
resistance and the lack of broad-spectrum virus-targeting drugs are still important issues and …
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen
A Maitra, T Munshi, J Healy, LT Martin… - FEMS microbiology …, 2019 - academic.oup.com
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis,
remains one of the leading causes of mortality across the world. There is an urgent …
remains one of the leading causes of mortality across the world. There is an urgent …
Natural cinnamic acids, synthetic derivatives and hybrids with antimicrobial activity
JD Guzman - Molecules, 2014 - mdpi.com
Antimicrobial natural preparations involving cinnamon, storax and propolis have been long
used topically for treating infections. Cinnamic acids and related molecules are partly …
used topically for treating infections. Cinnamic acids and related molecules are partly …
The changing paradigm of drug-resistant tuberculosis treatment: successes, pitfalls, and future perspectives
N Dookie, SL Ngema, R Perumal… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Drug-resistant tuberculosis (DR-TB) remains a global crisis due to the increasing incidence
of drug-resistant forms of the disease, gaps in detection and prevention, models of care, and …
of drug-resistant forms of the disease, gaps in detection and prevention, models of care, and …
Tuberculosis treatment and management—an update on treatment regimens, trials, new drugs, and adjunct therapies
A Zumla, J Chakaya, R Centis, L D'Ambrosio… - The Lancet …, 2015 - thelancet.com
WHO estimates that 9 million people developed active tuberculosis in 2013 and 1· 5 million
people died from it. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) …
people died from it. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) …
New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects
About 1· 3 million people died of tuberculosis in 2012, despite availability of effective drug
treatment. Barriers to improvements in outcomes include long treatment duration (resulting …
treatment. Barriers to improvements in outcomes include long treatment duration (resulting …
Totally drug‐resistant tuberculosis and adjunct therapies
SK Parida, R Axelsson‐Robertson… - Journal of internal …, 2015 - Wiley Online Library
The first cases of totally drug‐resistant (TDR) tuberculosis (TB) were reported in Italy 10
years ago; more recently, cases have also been reported in Iran, India and South Africa …
years ago; more recently, cases have also been reported in Iran, India and South Africa …
Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review
SHE Kaufmann, C Lange, M Rao, KN Balaji… - The Lancet …, 2014 - thelancet.com
Tuberculosis continues to kill 1· 4 million people annually. During the past 5 years, an
alarming increase in the number of patients with multidrug-resistant tuberculosis and …
alarming increase in the number of patients with multidrug-resistant tuberculosis and …
Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs
Tuberculosis is one of the deadliest infectious diseases existing in the world since ancient
times and still possesses serious threat across the globe. Each year the number of cases …
times and still possesses serious threat across the globe. Each year the number of cases …
Potential repurposed drug candidates for tuberculosis treatment: progress and update of drugs identified in over a decade
The devastating impact of Tuberculosis (TB) has been a menace to mankind for decades.
The World Health Organization (WHO) End TB Strategy aims to reduce TB mortality up to …
The World Health Organization (WHO) End TB Strategy aims to reduce TB mortality up to …