Antimicrobial resistance: a growing serious threat for global public health
Antibiotics are among the most important discoveries of the 20th century, having saved
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …
[HTML][HTML] Conventional methods and future trends in antimicrobial susceptibility testing
Antimicrobial susceptibility testing is an essential task for selecting appropriate antimicrobial
agents to treat infectious diseases. Constant evolution has been observed in methods used …
agents to treat infectious diseases. Constant evolution has been observed in methods used …
Design, synthesis, molecular docking, molecular dynamic simulation, and MMGBSA analysis of 7-O-substituted 5-hydroxy flavone derivatives
A series of chrysin derivatives were designed, synthesized, and evaluated for their
antibacterial activity against four different bacterial strains. We have synthesized new propyl …
antibacterial activity against four different bacterial strains. We have synthesized new propyl …
TRP channels in tumoral processes mediated by oxidative stress and inflammation
The channels from the superfamily of transient receptor potential (TRP) activated by reactive
oxygen species (ROS) can be defined as redox channels. Those with the best exposure of …
oxygen species (ROS) can be defined as redox channels. Those with the best exposure of …
Quadra-stable dynamics of p53 and PTEN in the DNA damage response
Cell fate determination is a complex process that is frequently described as cells traveling on
rugged pathways, beginning with DNA damage response (DDR). Tumor protein p53 (p53) …
rugged pathways, beginning with DNA damage response (DDR). Tumor protein p53 (p53) …
[HTML][HTML] Effect of quercetin and chrysin and its association on viability and cell cycle progression in MDA-MB-231 and MCF-7 human breast cancer cells
PS Ramos, C Ferreira, CLA Passos, JL Silva… - Biomedicine & …, 2024 - Elsevier
Pharmacological properties of flavonoids have been reported, with an anticancer role
amongst them, however, its mechanisms are not fully elucidated. In this study, the activity of …
amongst them, however, its mechanisms are not fully elucidated. In this study, the activity of …
Double C-2 like domain beta (DOC2B) induces calcium dependent oxidative stress to promote lipotoxicity and mitochondrial dysfunction for its tumor suppressive …
Mitochondria are biosynthetic and bioenergetic organelles that regulate many biological
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …
processes, including metabolism, oxidative stress, and cell death. Cervical cancer (CC) cells …
Combating antimicrobial resistance: the silent war
L Bo, H Sun, YD Li, J Zhu, JND Wurpel, H Lin… - Frontiers in …, 2024 - frontiersin.org
Once hailed as miraculous solutions, antibiotics no longer hold that status. The excessive
use of antibiotics across human healthcare, agriculture, and animal husbandry has given …
use of antibiotics across human healthcare, agriculture, and animal husbandry has given …
[PDF][PDF] Antimicrobial Resistance: A Growing Serious Threat for Global Public Health. Healthcare 2023, 11, 1946
Antibiotics are among the most important discoveries of the 20th century, having saved
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …
millions of lives from infectious diseases. Microbes have developed acquired antimicrobial …
JNJ-64619178 radiosensitizes and suppresses fractionated ionizing radiation-induced neuroendocrine differentiation (NED) in prostate cancer
Background Radiation therapy (RT) is a standard treatment regimen for locally advanced
prostate cancer; however, its failure results in tumor recurrence, metastasis, and cancer …
prostate cancer; however, its failure results in tumor recurrence, metastasis, and cancer …