The lens of the eye has long been considered as a radiosensitive tissue, but recent research
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …

Over 100 million individuals are affected by irreversible visual impairments and blindness
worldwide, while ocular diseases remain a challenging problem despite significant …

Lens homeostasis and transparency are dependent on the function and intercellular
communication of its epithelia. While the lens epithelium is uniquely equipped with …

Cataract is the leading cause of blindness worldwide. Cataract phacoemulsification
combined with intraocular lens implantation causes great burden to global healthcare …

Cellular senescence is a major hurdle for primary cell-based tissue engineering and
regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes …

Recent research shows that energy metabolism can strongly influence proteostasis and
thereby affect onset of aging and related disease such as Parkinson's disease (PD) …

The magnitude of cataract pathology is indeed significant as it is the principal cause of
blindness worldwide. Also, the prominence of this concept escalates with the current aging …

Background. Oxidative stress has been reported to be an early factor in the development of
cataracts. Echinatin (Ech) is an active ingredient of licorice that exhibits antioxidant effects …

Evidence from experimental and clinical studies indicates that oxidative stress plays a
critical role in the initiation and progression of many diseases. In this Chapter, we provide an …

Ergothioneine (ERGO) is a rare amino acid mostly found in fungi, including mushrooms, with
recognized antioxidant activity to protect tissues from damage by reactive oxygen species …