[HTML][HTML] HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Incidence and risk factors for prediabetes and diabetes mellitus among HIV-infected adults on antiretroviral therapy: a systematic review and meta-analysis

JR Nansseu, JJ Bigna, AD Kaze, JJ Noubiap - Epidemiology, 2018 - journals.lww.com
Objective: To summarize evidence on the rates and drivers of progression from
normoglycemia to prediabetes and/or diabetes mellitus (hereafter “diabetes”) in antiretroviral …

HIV, antiretroviral treatment, hypertension, and stroke in Malawian adults: a case-control study

LA Benjamin, EL Corbett, MD Connor, H Mzinganjira… - Neurology, 2016 - AAN Enterprises
Objective: To investigate HIV, its treatment, and hypertension as stroke risk factors in
Malawian adults. Methods: We performed a case-control study of 222 adults with acute …

[HTML][HTML] Contemporary disengagement from antiretroviral therapy in Khayelitsha, South Africa: a cohort study

SR Kaplan, C Oosthuizen, K Stinson, F Little… - PLOS …, 2017 - journals.plos.org
Background Retention in care is an essential component of meeting the UNAIDS “90-90-90”
HIV treatment targets. In Khayelitsha township (population~ 500,000) in Cape Town, South …

HIV Treatment and Associated Mitochondrial Pathology: Review of 25 Years of in Vitro, Animal, and Human Studies

K Gardner, PA Hall, PF Chinnery… - Toxicologic …, 2014 - journals.sagepub.com
Antiretroviral therapy has dramatically reduced mortality in human immunodeficiency virus
(HIV) infection. In 1988, the suggestion that the first antiretroviral drug, zidovudine, was the …

Prevalence, risk factors, and pathophysiology of Dysglycemia among people living with HIV in Sub‐Saharan Africa

B Njuguna, J Kiplagat, GS Bloomfield… - Journal of diabetes …, 2018 - Wiley Online Library
Objective. To review available literature on the prevalence, risk factors, pathophysiology,
and clinical outcomes of dysglycemia among people living with HIV (PLHIV) in sub‐Saharan …

Anti-HIV drugs cause mitochondrial dysfunction in monocyte-derived macrophages

J Wallace, H Gonzalez, R Rajan… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Combination antiretroviral therapy (cART) dramatically changed the face of the HIV/AIDS
pandemic, making it one of the most prominent medical breakthroughs of the past 3 …

[HTML][HTML] HIV-Related myocardial fibrosis: Inflammatory hypothesis and crucial role of immune cells dysregulation

E Teer, L Dominick, NC Mukonowenzou, MF Essop - Cells, 2022 - mdpi.com
Although the underlying mechanisms driving human immunodeficiency virus (HIV)-mediated
cardiovascular diseases (CVD) onset and progression remain unclear, the role of chronic …

[HTML][HTML] Dyslipidemia among rural and urban HIV patients in south-east Malawi

A Amberbir, V Singano, A Matengeni, Z Ismail… - PLoS …, 2018 - journals.plos.org
Background While dyslipidemia importantly contributes to increased cardiovascular disease
risk among patients on antiretroviral therapy (ART), data on lipid patterns among African …

Peripheral neuropathy in HIV patients in sub-Saharan Africa failing first-line therapy and the response to second-line ART in the EARNEST trial

A Arenas-Pinto, J Thompson, G Musoro… - Journal of …, 2016 - Springer
Sensory peripheral neuropathy (PN) remains a common complication in HIV-positive
patients despite effective combination anti-retroviral therapy (ART). Data on PN on second …